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Praziquantel: Understanding its Mechanism and Applications in Pharmaceutical Research

Praziquantel, a synthetic chemical compound with the CAS number 55268-74-1, is a cornerstone in the treatment of parasitic flatworm infections. Its efficacy against diseases like schistosomiasis, caused by schistosomes, and various cestode infestations makes it invaluable. Beyond its direct therapeutic use, praziquantel serves as a critical tool in pharmaceutical research and development. At NINGBO INNO PHARMCHEM CO.,LTD., we provide high-purity praziquantel for scientists engaged in discovering novel treatments and understanding the intricacies of parasitic diseases.

The precise action of praziquantel involves its impact on the parasite's cellular integrity. It rapidly increases the permeability of the parasite's cell membrane to calcium ions, leading to a rapid influx of extracellular calcium. This influx disrupts the worm's motor function, causing paralysis and increased susceptibility to mechanical damage by the host's immune system. This detailed understanding of its praziquantel mechanism of action is fundamental for researchers aiming to develop new anthelmintic drugs or modify existing ones. The availability of praziquantel for research use is crucial for advancing these efforts.

In pharmaceutical research, praziquantel is often used as a reference compound. Scientists study its chemical structure and biological activity to design new molecules with improved efficacy, broader spectrum, or reduced side effects. The praziquantel chemical synthesis is a key area of interest for optimizing production and ensuring consistent quality. The ability to buy praziquantel online from reputable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures researchers have access to reliable materials for their experiments.

Furthermore, praziquantel plays a role in understanding praziquantel drug resistance mechanisms. As parasites evolve, resistance to praziquantel can emerge, necessitating ongoing research to identify its causes and develop counter-strategies. Studying this resistance helps in the development of combination therapies or entirely new classes of anthelmintics. This research is vital for long-term disease control efforts.

The compound is also utilized as a pharmaceutical reference standard. Pharmaceutical companies rely on these standards for quality control during the manufacturing process, ensuring that the final drug product meets stringent purity and potency requirements. The rigorous testing and characterization of praziquantel by suppliers like NINGBO INNO PHARMCHEM CO.,LTD. are essential for its accurate use in analytical laboratories.

In conclusion, praziquantel's significance extends far beyond its immediate therapeutic applications. Its role as a research chemical, a standard for quality control, and a subject of study for understanding drug resistance makes it indispensable in the field of pharmaceutical research. NINGBO INNO PHARMCHEM CO.,LTD. is proud to support the scientific community by providing high-quality praziquantel, fostering innovation in the development of treatments for parasitic diseases.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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