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Premium Rosiptor (AQX-1125) API: A Potent Anti-Inflammatory Solution

NINGBO INNO PHARMCHEM CO.,LTD. is proud to present a high-quality Active Pharmaceutical Ingredient (API), CAS 782487-28-9, widely recognized as Rosiptor or AQX-1125. This advanced compound represents a significant advancement in pharmaceutical research, primarily valued for its distinct anti-inflammatory properties and its role as a selective activator of SHIP1 (Src homology 2 domain-containing inositol 5-phosphatase 1).


Rosiptor is a white to off-white crystalline powder with a molecular formula of C20H35NO2 and a molecular weight of 321.51. Its chemical integrity and purity, typically exceeding 98-99%, are rigorously maintained to meet the stringent demands of pharmaceutical development and research. The compound exhibits predictable boiling and density characteristics, crucial for its handling and formulation into various drug candidates.


The core mechanism of Rosiptor's action lies in its ability to activate SHIP1, a phosphatase predominantly expressed in immune cells derived from bone marrow tissues. By activating SHIP1, Rosiptor plays a crucial role in controlling the PI3K cellular signaling pathway. An overactive PI3K pathway can lead to excessive inflammation, characterized by the abundant production of pro-inflammatory signaling molecules and the accumulation of immune cells in tissues. Through its precise modulation of SHIP1, Rosiptor effectively inhibits Akt phosphorylation, reduces the production of various inflammatory mediators, and suppresses leukocyte chemotaxis in vitro. This targeted approach leverages a natural mechanism to maintain immune system homeostasis, offering a sophisticated anti-inflammatory effect without compromising cell viability at therapeutic concentrations.


The therapeutic potential of Rosiptor has been extensively explored in clinical trials and preclinical studies. It has shown promising results in addressing a range of inflammatory conditions, including chronic obstructive pulmonary disease (COPD), atopic dermatitis, interstitial cystitis, and bladder pain syndrome. In animal models, oral administration of Rosiptor has demonstrated a significant reduction in inflammatory markers and leukocyte accumulation, highlighting its strong in vivo efficacy. Its favorable pharmacokinetic profile, including good oral bioavailability, further underscores its potential as an orally active therapeutic agent.


As a leading manufacturer and supplier of advanced pharmaceutical chemicals, NINGBO INNO PHARMCHEM CO.,LTD. ensures that our Rosiptor (AQX-1125) API adheres to the highest quality standards, including GMP, FDA, and ISO certifications where applicable. We are committed to providing premium-grade materials that empower global buyers in their research and development endeavors. For those looking to buy or purchase this essential API, we offer competitive price options designed to facilitate access for diverse project scales, from laboratory research to larger-scale production. Our dedicated team is ready to provide comprehensive support and detailed product information to meet your specific requirements.


For more details on Rosiptor (AQX-1125) API, including pricing and availability, please contact NINGBO INNO PHARMCHEM CO.,LTD. We are your reliable partner for high-quality pharmaceutical intermediates and APIs, ensuring excellence and innovation in every product we offer.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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