Procaine Hydrochloride (HCl), a prominent member of the amino ester class of local anesthetics, is a compound with significant importance in both the medical and chemical industries. Its well-defined chemical properties, coupled with its therapeutic efficacy, make it a sought-after raw material for various applications. Understanding these aspects is crucial for anyone involved in its procurement or use.

Chemically, Procaine HCl is the hydrochloride salt of procaine, with the molecular formula C13H20N2O2·HCl and CAS number 51-05-8. It typically presents as a white or almost white crystalline powder. Its solubility in water and ethanol facilitates its formulation into various pharmaceutical preparations. The compound's structure features an aromatic amine group linked via an ester group to a diethylaminoethyl chain, which is fundamental to its anesthetic activity.

The primary application of Procaine HCl is as a local anesthetic. Its mechanism involves blocking voltage-gated sodium channels on neuronal membranes, thereby inhibiting the transmission of pain signals. It is widely used in dentistry, minor surgical procedures, and for nerve blocks. The compound's relatively low toxicity and rapid metabolism contribute to its favorable safety profile when administered correctly.

Beyond its direct anesthetic use, Procaine HCl serves as a critical intermediate in the synthesis of other pharmaceuticals. A notable example is its combination with penicillin to form procaine penicillin. This formulation extends the duration of antibiotic activity and reduces pain associated with intramuscular injections. This dual role underscores the compound's versatility and demand within the pharmaceutical sector.

For procurement professionals looking to purchase Procaine HCl, identifying reliable manufacturers is key. Sourcing from established chemical companies, particularly those in regions with strong pharmaceutical intermediate production capabilities like China, can ensure access to high-purity material at competitive prices. When evaluating suppliers, it is essential to scrutinize product specifications, including purity (typically >99%), CAS number, and compliance with pharmacopoeial standards (USP, BP, EP). Requesting Certificates of Analysis (COA) for each batch is a standard procedure.

The availability of Procaine HCl in different forms, such as powder or crystalline powder, and various packaging sizes (e.g., grams for research, kilograms for industrial use) caters to diverse customer needs. For those seeking to buy Procaine HCl powder, confirming the exact specifications and origin from the manufacturer is paramount for quality assurance and regulatory compliance. Understanding the Procaine HCl price will depend on factors such as purity, quantity, and the supplier's location and manufacturing standards.

In conclusion, Procaine HCl is a chemically well-defined compound with significant therapeutic and industrial value. Its role as a local anesthetic and a pharmaceutical intermediate necessitates careful sourcing from reputable manufacturers to ensure quality and efficacy.