Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
For procurement managers and R&D scientists in the pharmaceutical sector, sourcing high-quality intermediates like 5,6-Diphenyl-2-hydroxypyrazine (CAS: 18591-57-6) is paramount. This compound serves as a critical building block in the synthesis of Selexipag, a significant medication for pulmonary arterial hypertension. Ensuring a consistent supply of a pure intermediate directly impacts the efficacy and safety of the final API. This guide focuses on what B2B buyers should look for when seeking to purchase this essential chemical from manufacturers and suppliers, particularly those based in China.
Understanding Purity and Specifications:
The primary specification for 5,6-Diphenyl-2-hydroxypyrazine is its purity, typically requiring an assay of ≥98.0%. This level of purity is essential to minimize unwanted side reactions and impurities in the subsequent Selexipag synthesis. Look for suppliers who provide detailed Certificates of Analysis (CoA) that clearly state the assay, appearance (white to light yellow powder), and other relevant physical and chemical properties such as molecular formula (C16H12N2O) and molecular weight (248.27900). A supplier's ability to consistently meet these specifications is a strong indicator of their manufacturing capabilities.
Supplier Reliability and Manufacturing Capability:
When looking to buy 5,6-Diphenyl-2-hydroxypyrazine, it’s crucial to partner with reliable manufacturers. A reputable 5,6-Diphenyl-2-hydroxypyrazine manufacturer in China will have robust quality control systems, modern production facilities, and a proven track record in producing pharmaceutical intermediates. Consider factors like their capacity for bulk supply, lead times, and their commitment to regulatory compliance. Companies that offer custom synthesis services or have established partnerships with larger production facilities often provide greater assurance of consistent supply, from kilos to tons.
Price and Market Considerations:
The price of 5,6-Diphenyl-2-hydroxypyrazine can vary based on purity, order volume, and supplier. While cost-effectiveness is important, it should not compromise quality. Buyers are encouraged to request quotes from multiple suppliers to get a clear understanding of the market price for this pharmaceutical intermediate. Understanding the market dynamics and availability from different regions, including India and China, can help in negotiating favorable terms. By prioritizing a balance between quality and competitive pricing, procurement managers can secure a stable supply chain for their Selexipag manufacturing needs.
For businesses seeking a dependable source for 5,6-Diphenyl-2-hydroxypyrazine, focusing on these key aspects – purity, supplier reliability, and informed pricing strategies – will lead to successful procurement. Companies that can offer consistent quality, scalable manufacturing, and transparent dealings are ideal partners in the competitive pharmaceutical landscape.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
