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Procuring Ethyl 3,4-Dihydroxybenzoate: A Buyer's Guide for Pharmaceutical Intermediates

For procurement managers and R&D scientists in the pharmaceutical sector, the efficient and reliable sourcing of chemical intermediates is a cornerstone of successful drug development and manufacturing. Ethyl 3,4-Dihydroxybenzoate (CAS: 3943-89-3) is a prime example of such a critical intermediate, essential for the synthesis of vital therapeutic agents like Erlotinib. This guide outlines key considerations when looking to procure this compound.

Understanding the product is the first step. Ethyl 3,4-Dihydroxybenzoate, with synonyms like Ethyl Protocatechuate, boasts a molecular formula of C9H10O4 and a molecular weight of 182.17300. It typically appears as a white crystalline powder, with purity specifications commonly set at ≥99%. Its well-defined physical and chemical properties, including a melting point of 132-134 °C, are critical indicators of quality for pharmaceutical applications. When you intend to 'buy' this substance, scrutinizing these details provided by potential suppliers is non-negotiable.

The primary application driving demand for Ethyl 3,4-Dihydroxybenzoate is its role as a key intermediate in the synthesis of Erlotinib and its hydrochloride salt. These drugs are used in targeted cancer therapies, meaning the quality of the intermediate directly impacts the final API's efficacy and safety. Therefore, identifying a 'reliable pharmaceutical intermediate supplier' is crucial. Look for manufacturers who can provide a consistent supply and detailed Certificates of Analysis (CoA) with each batch.

When evaluating 'Ethyl 3,4-Dihydroxybenzoate price', it’s important to consider the total value proposition, not just the per-kilogram cost. Factors such as purity, lead times, packaging options, and the supplier's regulatory compliance and support capabilities significantly influence the overall value. A trustworthy 'manufacturer in China' will often offer competitive pricing for bulk purchases, alongside excellent technical support and reliable logistics.

For those seeking to 'purchase pharmaceutical raw materials', engaging with experienced chemical companies is recommended. These companies often have extensive R&D facilities and robust production capabilities, allowing them to cater to diverse project needs, from small-scale laboratory requirements to large-volume commercial manufacturing. Establishing a partnership with a supplier that understands your specific project needs and can offer tailored solutions, such as custom packaging or specific analytical data, is highly beneficial.

In essence, procuring Ethyl 3,4-Dihydroxybenzoate requires a strategic approach. By focusing on purity, supplier reliability, competitive pricing, and comprehensive support, procurement professionals can secure this vital intermediate for their Erlotinib synthesis projects. Partnering with reputable manufacturers ensures a stable and high-quality supply chain, essential for bringing life-saving treatments to market.

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