For chemists and material scientists, a deep understanding of a chemical intermediate's properties is the bedrock of successful synthesis. 1,1,1-Trifluoro-4-iodobutane (CAS: 461-17-6) is a prime example of a fluorinated organic compound whose specific characteristics make it invaluable in diverse chemical transformations. Whether you are involved in pharmaceutical development, agrochemical innovation, or material science, grasping its properties is key to effective utilization.

Physically, 1,1,1-Trifluoro-4-iodobutane is described as a clear liquid, often with a pale yellow or light orange tint. Its molecular formula is C4H6F3I, and its molecular weight is approximately 237.99 g/mol. Key physical properties often noted by manufacturers and suppliers include a boiling point around 126-128°C and a flash point typically above 100°C (though some sources cite closer to 42.5°C with a ±5.6°C variance, indicating careful handling is always advised). These properties suggest moderate volatility and that it should be handled with appropriate safety precautions, especially concerning ignition sources.

Chemically, the compound's structure is critical. It features a four-carbon chain with a trifluoromethyl group (-CF3) at one end and an iodine atom at the other. The highly electronegative fluorine atoms in the trifluoromethyl group significantly influence the electron distribution within the molecule, often increasing polarity and affecting reactivity. The iodine atom, being a good leaving group, makes this compound an excellent substrate for nucleophilic substitution reactions and various cross-coupling reactions, such as Suzuki, Sonogashira, or Heck couplings. These reactions are fundamental in organic synthesis for forming new carbon-carbon bonds.

The purity of 1,1,1-Trifluoro-4-iodobutane is a critical parameter that impacts its performance. A typical specification of ≥98.0% GC purity ensures that the compound is largely free from impurities that could interfere with sensitive reactions or contaminate final products. For researchers aiming to buy this chemical for demanding applications, such as the synthesis of Active Pharmaceutical Ingredients (APIs) or advanced agrochemicals, partnering with a supplier that consistently delivers high-purity material is essential. We, as a dedicated supplier, ensure our product meets these exacting standards.

Understanding these properties allows chemists to effectively plan synthesis routes, predict reaction outcomes, and optimize experimental conditions. Whether you are performing fluorination reactions or utilizing it as a building block, knowing the physical and chemical characteristics of 1,1,1-Trifluoro-4-iodobutane from a reliable manufacturer is the first step towards successful outcomes. We invite you to inquire about our competitively priced 1,1,1-Trifluoro-4-iodobutane and leverage its capabilities in your next synthesis project.