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Understanding the Properties of 2-Chloroquinoline-3-Carbaldehyde: A Chemical Profile

For chemists and researchers working with specialized organic molecules, a thorough understanding of a compound's physical and chemical properties is fundamental to successful synthesis and application. 2-Chloroquinoline-3-Carbaldehyde (CAS: 73568-25-9) is one such compound, a versatile intermediate whose properties dictate its reactivity and suitability for various chemical transformations. As a professional chemical supplier, we aim to provide clear and accurate information about this crucial compound.

The most immediately observable characteristic of 2-Chloroquinoline-3-Carbaldehyde is its appearance. Typically, it presents as a yellow to yellow-brown crystalline powder. This visual cue is often the first indicator of product quality and consistency. The crystalline nature suggests a well-defined molecular structure, essential for predictable chemical behavior.

Delving into its physical constants, the melting point is a key parameter. 2-Chloroquinoline-3-Carbaldehyde has a reported melting point range of approximately 148-150 °C. This relatively high melting point signifies a stable solid form under standard laboratory conditions and is an important factor for handling, storage, and reaction temperature considerations. Variations in this range can sometimes indicate the presence of impurities.

Solubility is another critical property that influences reaction setup and work-up procedures. 2-Chloroquinoline-3-Carbaldehyde exhibits limited solubility in common organic solvents like chloroform and ethyl acetate. This characteristic guides chemists in selecting appropriate reaction media and crystallization solvents for purification. Understanding these solubility patterns is crucial when planning synthesis routes that involve this intermediate.

The chemical formula, C10H6ClNO, and a molecular weight of 191.61 g/mol provide foundational data for stoichiometric calculations. The presence of a chlorine atom and an aldehyde group on the quinoline ring system imbues this molecule with significant reactivity. The aldehyde group can participate in numerous carbonyl chemistry reactions, such as Wittig reactions, Grignard additions, and reductive aminations, while the chlorine atom can undergo nucleophilic aromatic substitution reactions. This dual reactivity makes it an indispensable intermediate for constructing more complex heterocyclic compounds.

As a supplier, we ensure that our 2-Chloroquinoline-3-Carbaldehyde meets a high purity standard, often 97% or greater, to facilitate its effective use in demanding synthetic applications. Researchers and procurement specialists seeking this compound will find that detailed property information, coupled with a reliable source, is essential for project success. We encourage you to inquire about our product specifications and pricing for this valuable chemical intermediate.

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