For chemists engaged in organic synthesis, a thorough understanding of the properties of their starting materials and intermediates is fundamental to designing successful reaction pathways. 2-Methoxy-5-(trifluoromethyl)pyridine (CAS 175277-45-9) is one such compound, prized for its utility as a building block. This article explores its key physical and chemical characteristics, offering insights for researchers and procurement managers looking to buy this essential chemical.

Chemical Identity and Specifications
Chemical Name: 2-Methoxy-5-(trifluoromethyl)pyridine
CAS Number: 175277-45-9
Molecular Formula: C7H6F3NO
Molecular Weight: 177.12400
Appearance: White crystalline powder
Assay: ≥99.0%
Moisture: ≤1.0%

The high purity level (≥99.0%) is a critical specification, ensuring minimal interference from impurities in demanding synthetic applications. The low moisture content (≤1.0%) also contributes to its stability and reactivity predictability.

Physical and Chemical Properties
Understanding the physical state and thermal properties of a chemical intermediate is vital for handling, storage, and reaction design.

• Melting Point: 104-106°C. This relatively high melting point indicates it is a stable solid at room temperature, making it easier to handle and measure compared to liquids. This range is also indicative of its purity.
• Boiling Point: 166.6°C. The boiling point is relevant for distillation or other high-temperature processes, providing an important parameter for process optimization.
• Density: 1.263. This value is useful for calculations involving volume and mass, particularly in process scale-up.
• Flash Point: 123°F (approximately 50.5°C). While the provided value is for a similar compound, the presence of flammable properties needs to be considered for safe handling and storage. For 2-Methoxy-5-(trifluoromethyl)pyridine, specific safety data sheets should always be consulted.

Handling and Storage Recommendations
As a high-purity crystalline powder, 2-Methoxy-5-(trifluoromethyl)pyridine should be stored in a cool, well-ventilated place, away from incompatible materials. Proper packaging, typically in 25 kg drums or according to customer requirements, ensures its integrity. Always refer to the manufacturer's specific storage guidelines.

Sourcing and Purchasing Information
When you are ready to buy 2-Methoxy-5-(trifluoromethyl)pyridine, it is crucial to partner with a reputable supplier who can guarantee these specifications. NINGBO INNO PHARMCHEM CO.,LTD. offers this compound with guaranteed purity and provides comprehensive technical data. To obtain pricing or discuss your specific needs, initiating an inquiry is the best approach. Our team is ready to assist you in sourcing this valuable intermediate for your organic synthesis projects.

By understanding the detailed properties of 2-Methoxy-5-(trifluoromethyl)pyridine, chemists and procurement professionals can make informed decisions, ensuring the successful and efficient execution of their synthetic strategies.