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For chemists and material scientists, a thorough understanding of a chemical intermediate's properties is crucial for optimizing synthesis and developing innovative applications. 3-Bromothiophene-2-carboxylic Acid (CAS: 7311-64-0) is a prime example, offering a unique combination of functional groups that make it a versatile tool in organic chemistry. When you decide to buy this compound, familiarizing yourself with its key characteristics will empower your research and development efforts.
The chemical structure of 3-Bromothiophene-2-carboxylic Acid features a thiophene ring, a five-membered aromatic heterocycle containing sulfur. This ring system itself imparts specific electronic properties and reactivity. Attached to this ring are two key functional groups: a bromine atom at the 3-position and a carboxylic acid group at the 2-position. The bromine atom is an excellent leaving group, making it highly amenable to various cross-coupling reactions, which are foundational in modern organic synthesis. This allows for the facile introduction of diverse substituents onto the thiophene core.
The carboxylic acid group (-COOH) provides another avenue for chemical modification. It can undergo esterification, amidation, or reduction, further expanding the synthetic utility of 3-Bromothiophene-2-carboxylic Acid. This dual functionality – reactivity at the bromine site and modification potential at the carboxylic acid site – makes it a powerful building block for creating more complex molecules. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. often specify a high purity (97% min) for this intermediate, ensuring that these reactive sites function as intended in your synthetic strategies.
Key physical properties also play a role in its handling and application. With a melting point typically in the range of 197-201 °C, it exists as a solid under standard laboratory conditions, usually appearing as a white to almost white powder or crystal. This physical form is generally easy to handle and measure. When considering to purchase 3-Bromothiophene-2-carboxylic Acid for your projects, understanding these properties will help you integrate it effectively into your experimental designs, whether for pharmaceutical intermediates, material science, or advanced organic synthesis.
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