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Understanding the Properties and Handling of 2-Cyano-5-fluoropyridine

For professionals in the chemical and pharmaceutical industries, a thorough understanding of the properties and safe handling procedures for chemical intermediates is crucial. This article focuses on 2-Cyano-5-fluoropyridine (CAS 327056-62-2), detailing its key physical and chemical characteristics, and providing essential guidance on its safe handling, storage, and disposal. Sourcing this compound from a reputable manufacturer ensures access to accurate safety data.

Physical and Chemical Properties of 2-Cyano-5-fluoropyridine

2-Cyano-5-fluoropyridine (Molecular Formula: C6H3FN2, Molecular Weight: 122.10) typically presents as a white powder. Its purity is often specified at 95% min or 98% min, making it suitable for sensitive synthetic applications. The presence of the nitrile group and the fluorine atom on the pyridine ring dictates its chemical reactivity. While specific details on its density (1.24 g/cm³) and flash point (83.8 °C) are available, its solubility characteristics and detailed reactivity profiles are best consulted from the Material Safety Data Sheet (MSDS) provided by the supplier.

Its melting point is noted as 35-41 °C, suggesting it is a solid at typical room temperatures. The compound is also characterized by its molecular structure, which is critical for chemists designing synthetic routes. Its CAS number, 327056-62-2, is the universal identifier for this specific chemical entity.

Safe Handling and Storage Best Practices

Given its classification under hazard symbols like 'Harmful Xn' and 'Dangerous N', proper handling of 2-Cyano-5-fluoropyridine is imperative. When you buy this chemical, ensure you are equipped with appropriate personal protective equipment (PPE), including safety goggles, chemical-resistant gloves, and protective clothing. Work in a well-ventilated area, preferably a fume hood, to minimize inhalation exposure.

Key handling precautions include:

  • Avoid contact with skin, eyes, and clothing.
  • Do not ingest or inhale.
  • Wash hands thoroughly after handling.
  • Ensure containers are tightly sealed when not in use.

Storage conditions are also critical to maintain the compound's integrity and ensure safety. It should be stored in a cool, dry, and well-ventilated place, away from incompatible materials such as strong oxidizing agents. Keeping the container tightly closed will prevent moisture absorption and potential degradation.

Disposal Considerations

Dispose of 2-Cyano-5-fluoropyridine and its containers in accordance with local, regional, and national regulations. Consult the MSDS for specific disposal recommendations. Never dispose of chemicals down the drain or into the environment.

By understanding and adhering to these guidelines, chemical professionals can safely and effectively utilize 2-Cyano-5-fluoropyridine in their work. For those looking to purchase this intermediate, sourcing from a reputable manufacturer with comprehensive safety documentation is a vital first step.

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