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Understanding the Properties and Applications of 5-Cyanophthalide (CAS 82104-74-3)

5-Cyanophthalide, a compound identified by CAS number 82104-74-3, is a vital organic molecule that plays a significant role in the modern chemical and pharmaceutical industries. Its structure, featuring a phthalide ring fused with a cyano group, endows it with unique chemical reactivity, making it an invaluable intermediate for synthesizing complex compounds.

Chemically, 5-Cyanophthalide typically presents as a white to light yellow crystalline powder. Its key properties include a defined melting point, generally in the range of 200-205°C, and solubility in various organic solvents, though this can vary. These physical and chemical characteristics are crucial for its handling, storage, and effective use in synthetic processes. The compound's molecular formula is C9H5NO2, with a molecular weight of approximately 159.14 g/mol.

The synthesis of 5-Cyanophthalide usually involves precise chemical reactions, often starting from phthalic derivatives. Manufacturers continuously refine these processes to enhance yield, purity, and cost-effectiveness. Achieving high purity, often exceeding 98%, is a primary goal, as it directly impacts the success of subsequent reactions. For example, when used as a pharmaceutical intermediate, ensuring the absence of unwanted by-products is critical for patient safety and drug efficacy.

The primary application of 5-Cyanophthalide lies in its role as an intermediate in the synthesis of pharmaceuticals. It is a key component in the production of widely used antidepressants, such as Citalopram and Escitalopram. Beyond pharmaceuticals, it also finds use in various organic synthesis applications and the development of fine chemicals, where its reactive nature allows for the creation of intricate molecular structures. The ability to reliably source high-purity 5-Cyanophthalide, like that provided by NINGBO INNO PHARMCHEM CO.,LTD., is essential for researchers and manufacturers alike.

As the demand for sophisticated chemical compounds grows, understanding the specific properties and applications of intermediates like 5-Cyanophthalide becomes increasingly important. Its versatility as a building block solidifies its position as a cornerstone chemical for innovation in numerous industrial sectors.

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