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Understanding the Properties and Applications of 7-Azaindole-3-carboxaldehyde

7-Azaindole-3-carboxaldehyde, identified by its CAS number 4649-09-6, is a notable organic compound characterized by its distinct chemical structure and versatile properties. This compound, often appearing as a light yellow to off-white solid, has garnered significant attention in the fields of organic synthesis and pharmaceutical research due to its utility as a key intermediate.

Physically, 7-Azaindole-3-carboxaldehyde typically presents as a crystalline solid with a melting point in the range of 216-220 °C. This solid nature at room temperature, combined with its relatively high melting point, indicates a stable compound suitable for handling and storage under standard laboratory conditions. While precise density and boiling point data are often predicted, its molecular formula (C8H6N2O) and molecular weight (146.15 g/mol) are well-established, providing essential information for stoichiometric calculations in synthesis.

Chemically, the presence of the azaindole heterocyclic system and the aldehyde functional group are key to its reactivity. The aldehyde group is electrophilic and can undergo a variety of reactions, including nucleophilic additions, condensations, and oxidations/reductions. The azaindole core itself can also be subject to electrophilic aromatic substitution and metal-catalyzed cross-coupling reactions, allowing for extensive structural diversification.

These properties translate into a broad range of applications. 7-Azaindole-3-carboxaldehyde is widely employed as a building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its derivatives have shown promise in various therapeutic areas, including anticancer, antiviral, and anti-inflammatory applications. For researchers and procurement specialists looking to buy this compound, understanding these properties is crucial for selecting appropriate reaction conditions and ensuring successful synthesis outcomes. Sourcing from reliable manufacturers, particularly those in China known for their expertise in fine chemical production, can provide access to high-purity material (often >97%) at competitive prices, facilitating research and development efforts.

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