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Fluorinated organic compounds have garnered significant attention in various scientific disciplines due to the profound impact of fluorine atoms on molecular properties. Among these, fluorinated heterocycles represent a particularly important class, offering unique electronic, steric, and lipophilic characteristics. 5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine (CAS: 1034667-22-5) exemplifies the utility of such structures, serving as a versatile building block in modern chemical synthesis, especially within the pharmaceutical industry.
The incorporation of fluorine into organic molecules can dramatically alter their reactivity, acidity, basicity, and metabolic stability. In the case of 5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine, the presence of a fluorine atom on the pyrazolo[3,4-b]pyridine core can influence electron distribution, hydrogen bonding capabilities, and overall molecular conformation. These modifications are crucial for designing molecules with specific biological activities or desired material properties. Researchers looking to buy advanced chemical intermediates often seek out fluorinated heterocycles for their ability to fine-tune molecular behavior.
The pyrazolo[3,4-b]pyridine scaffold itself is a privileged structure found in many biologically active compounds. When functionalized with a fluorine atom and an amine group, as in 5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine, it becomes a potent precursor for a wide array of synthetic targets. Its most recognized application is as an intermediate in the production of Vericiguat, a drug for heart failure, highlighting its significance in pharmaceutical manufacturing. However, its potential extends beyond this single application, making it an attractive compound for broader research in medicinal chemistry and materials science.
As a reliable supplier of this specialized intermediate, we ensure that chemists and researchers have access to high-purity material (≥95%) for their work. Understanding the properties and potential applications of such compounds is key for innovation. Whether you are developing new pharmaceuticals, agrochemicals, or advanced materials, 5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine offers a valuable entry point for introducing complex fluorinated heterocyclic motifs. We encourage you to inquire about purchasing this compound and explore its potential in your next project.
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