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Understanding the Properties and Uses of Ethyl 2-bromo-3-methylbutyrate

Ethyl 2-bromo-3-methylbutyrate (CAS: 609-12-1) is a valuable organic compound that serves as a versatile intermediate in various chemical synthesis processes. Its unique combination of an ester group and an alkyl bromide makes it a sought-after building block in industries ranging from pharmaceuticals to agrochemicals. For procurement specialists and research scientists, understanding its properties and applications is fundamental when considering purchasing this chemical.

Key Physico-Chemical Properties

Ethyl 2-bromo-3-methylbutyrate is typically described as a colorless to pale yellow liquid. Its molecular formula is C7H13BrO2, with a molecular weight of approximately 209.08 g/mol. Key physical characteristics include a boiling point of around 77 °C at 12 mmHg and a flash point of approximately 65 °C. Its solubility in common organic solvents like chloroform, ethyl acetate, and hexane is noted, while its solubility in water is limited due to its hydrophobic nature. These properties are essential for handling, storage, and reaction planning.

Primary Applications in Chemical Synthesis

The primary utility of Ethyl 2-bromo-3-methylbutyrate lies in its role as a synthetic intermediate. Its reactive bromine atom makes it an excellent electrophile for nucleophilic substitution reactions, allowing for the introduction of diverse functional groups or the formation of new carbon-carbon bonds. This versatility makes it highly valuable in:

  • Pharmaceutical Synthesis: It acts as a crucial building block for creating complex APIs and drug candidates.
  • Agrochemical Production: It is used in the synthesis of various pesticides and crop protection chemicals.
  • Specialty Chemicals: Its structure can be incorporated into a wide range of specialty chemicals for diverse industrial applications.

Where to Buy and What to Consider

When you need to buy Ethyl 2-bromo-3-methylbutyrate, seeking out reputable manufacturers and suppliers is paramount. High purity (e.g., 99% min assay) is typically required for optimal performance in synthesis. Always check for product specifications and request safety data sheets (SDS) from potential suppliers. Many global buyers look to established chemical manufacturers for competitive pricing and reliable supply chains. When inquiring about purchasing, be prepared to specify the quantity and purity required. Requesting a quote from a trusted manufacturer will provide clarity on pricing and delivery terms.

In summary, Ethyl 2-bromo-3-methylbutyrate is a fundamental intermediate characterized by its useful physical properties and broad applications in organic synthesis. Its consistent availability from reliable sources ensures its continued importance in developing innovative chemical products across multiple industries.

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