NINGBO INNO PHARMCHEM CO.,LTD. is pleased to highlight the significance of Polyvinylpyrrolidone K30 (PVP K30) Pharma Grade, a highly versatile and widely used pharmaceutical excipient. Known by its CAS number 9003-39-8, PVP K30 is a synthetic polymer derived from N-vinylpyrrolidone. Its unique properties make it indispensable in numerous pharmaceutical formulations, enhancing stability, performance, and patient compliance.

PVP K30 Pharma Grade presents as a white to milky white powder. It is characterized by its excellent solubility in water and various organic solvents such as ethanol, isopropyl alcohol, and trichloromethane, while being insoluble in common solvents like acetone and ether. This broad solubility profile is crucial for its diverse applications in both solid and liquid dosage forms. Its hygroscopic nature requires appropriate storage conditions to maintain quality and efficacy over its shelf life.

The primary functions of PVP K30 in pharmaceuticals are multifaceted and critical. As a tablet binder, it imparts the necessary mechanical strength to tablets, preventing crumbling during manufacturing, handling, and storage. Its adhesive properties ensure that the powdered ingredients in a tablet formulation cohere properly under compression. Beyond binding, PVP K30 also serves effectively as a disintegrant in certain formulations, promoting the rapid break-up of tablets in the gastrointestinal tract, which is essential for quick drug release.

Furthermore, PVP K30 is highly valued as a dissolution enhancer, particularly for poorly water-soluble active pharmaceutical ingredients (APIs). By forming solid dispersions or complexes with such APIs, it can significantly improve their solubility and dissolution rate, leading to enhanced bioavailability. In liquid formulations, PVP K30 acts as an excellent suspending agent, helping to stabilize suspensions and prevent sedimentation of solid particles, ensuring uniform dosing throughout the product's shelf life.

The quality of PVP K30 Pharma Grade is paramount for pharmaceutical applications. Our product meets the stringent requirements of major international pharmacopoeias, including USP, BP, EP, and CP. Adherence to these standards guarantees consistency in critical parameters such as K-value (which reflects the molecular weight and thus viscosity and binding strength), moisture content, impurity levels (like aldehydes and 2-pyrrolidone), and nitrogen content. Such rigorous quality control ensures that the excipient performs reliably in pharmaceutical manufacturing processes and contributes positively to the final drug product's quality and safety.

Packaging of PVP K30 Pharma Grade is typically in 25kg fiber drums, designed to protect the material from environmental factors during transport and storage. Recommended storage conditions involve keeping the product in a cool, dry place below 30°C, shielded from humidity and physical pressure, to preserve its two-year validity period. Proper handling and storage are key to maintaining the powder's integrity and performance characteristics.

For pharmaceutical manufacturers and formulators seeking a reliable supply of high-quality PVP K30 Pharma Grade, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted manufacturer and supplier. We offer competitive price options based on order volume, catering to various production scales. Whether you need to buy for research & development or require bulk purchase for commercial production, our team is ready to provide detailed product information, specifications, and logistical support to meet your specific needs.