At NINGBO INNO PHARMCHEM CO.,LTD., we understand that selecting the right grade of Povidone is crucial for achieving optimal results in any formulation. Povidone, commonly known as PVP K-series, is characterized by its K-value, which directly correlates with its molecular weight and, consequently, its viscosity and adhesive properties. Understanding these K-values is key to unlocking the full potential of Povidone K90 (PVP K90) and its counterparts.
The K-value, derived from the Fikentscher K value, is a measure of the intrinsic viscosity of the polymer in an aqueous solution. This value is determined by the molecular weight of the Povidone chains. Generally, a higher K-value signifies a higher molecular weight and a greater degree of polymerization, leading to increased viscosity and enhanced adhesive strength. For instance, Povidone K15 has a lower molecular weight and viscosity compared to Povidone K30 and significantly less than Povidone K90.
Povidone K90, with its high K-value, possesses the highest molecular weight and therefore the greatest viscosity and adhesive power among the commonly used grades. This makes it an excellent choice for applications requiring strong binding, such as in tablet manufacturing where it can be used in lower concentrations (typically 1-3%) due to its high binding efficiency. Its high viscosity also lends itself to applications where thickening or sustained release properties are desired.
Conversely, lower K-value grades like Povidone K15, K25, and K30 have lower molecular weights and viscosities. Povidone K30, for example, is often used as a binder in tablet formulations at slightly higher concentrations (2-5%) and offers a good balance between adhesive strength and ease of handling. It is also effective as a solubilizing agent and stabilizer in various formulations. Povidone K15 and K17 are even lower in viscosity and are often preferred for applications where a less viscous solution is needed, such as in certain liquid formulations or as film formers in thinner coatings.
The choice between different Povidone grades, including PVP K90, depends entirely on the specific requirements of the application. Whether it’s the binding strength needed for solid dosage forms, the solubilizing capacity for poorly soluble drugs, or the film-forming properties for cosmetic products, selecting the appropriate K-value is paramount. NINGBO INNO PHARMCHEM CO.,LTD. provides a comprehensive range of Povidone grades, ensuring that formulators can precisely match the Povidone's characteristics to their product's performance objectives.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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