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In the world of pharmaceutical development, the quality and purity of active pharmaceutical ingredients (APIs) are paramount. However, the journey to a finished API begins much earlier, with the foundational intermediates that serve as its building blocks. One such critical raw material is 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile, identified by its CAS number 256376-65-5. This compound is an essential intermediate in the synthesis of Riociguat, a significant medication used in treating specific types of pulmonary hypertension.
Riociguat works as a soluble guanylate cyclase (sGC) stimulator, a novel mechanism that helps relax and widen blood vessels in the lungs, thereby lowering blood pressure and improving a patient's ability to exercise. The complex molecular structure of Riociguat requires a precise, multi-step synthesis process, and the integrity of each step is crucial for the final product's efficacy and safety. This is where the importance of high-quality intermediates like CAS 256376-65-5 comes into sharp focus. This intermediate provides the core pyrazolo[3,4-b]pyridine framework necessary for building the final Riociguat molecule.
Product Profile: Riociguat Intermediate CAS 256376-65-5
This intermediate is supplied as a yellow to dark yellow powder, ensuring stability and ease of handling in a laboratory or manufacturing environment. Its chemical formula is C₁₄H₉FN₄, with a molecular weight of 252.25 g/mol. At NINGBO INNO PHARMCHEM CO.,LTD., we ensure this product meets stringent quality standards, with consistent purity and minimal impurities. The reliability of this intermediate is fundamental to achieving high yields and a dependable safety profile in the final Riociguat API. Inconsistent quality in a starting material can lead to downstream complications, including difficult purifications and compromised final product integrity.
Our Commitment to Quality
NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to advancing pharmaceutical research and manufacturing by providing superior-grade chemical intermediates. We understand the critical nature of the supply chain in drug development and production. By offering this key Riociguat intermediate, we support our partners in their mission to produce life-changing medications. Our commitment extends from meticulous sourcing and synthesis to rigorous quality control, ensuring that every batch we deliver meets the high expectations of the pharmaceutical industry.
As a trusted manufacturer and supplier, we provide comprehensive support for your development needs. If you are looking to buy Riociguat Intermediate with CAS No. 256376-65-5 or require information on the price and availability for a bulk purchase, our team is ready to assist. Partner with us to secure a reliable source for this vital pharmaceutical raw material and ensure the success of your synthesis projects.
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