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The Role of 1-Methyl-L-4,5-dihydroorotic Acid in Pharmaceutical Synthesis

The intricate world of pharmaceutical synthesis relies heavily on specialized building blocks, often referred to as intermediates. Among these, 1-Methyl-L-4,5-dihydroorotic acid stands out for its specific role in the creation of important therapeutic agents. As a leading supplier of such fine chemicals, we understand the importance of detailing the utility and characteristics of compounds like this for our B2B clientele.

1-Methyl-L-4,5-dihydroorotic Acid: A Key Intermediate for Taltirelin

The primary application for 1-Methyl-L-4,5-dihydroorotic acid (CAS: 103365-69-1) is its function as a crucial intermediate in the synthesis of Taltirelin. Taltirelin is a drug that has been developed and used in Japan for improving ataxia in patients suffering from spinocerebellar ataxia. Its therapeutic effects are linked to endocrine and central nervous system actions. This makes the reliable supply of high-quality 1-Methyl-L-4,5-dihydroorotic acid essential for pharmaceutical companies engaged in the research, development, and manufacturing of such treatments.

Chemical Properties and Sourcing Considerations

Professionals looking to buy 1-Methyl-L-4,5-dihydroorotic acid will find that it is typically supplied as a white powder with a high purity level, often exceeding 99%. Its molecular formula C6H8N2O4 and molecular weight of 172.14 are standard identification parameters. The melting point range of 212-214°C is a key physical property. When sourcing this compound, it's important to consider its chirality, as indicated by the 'L' in its name and the (4S) designation in some synonyms, signifying its specific stereochemistry. This is critical for its biological activity.

Why Choose a Dedicated Supplier?

For researchers and procurement managers, selecting the right supplier for pharmaceutical intermediates is a strategic decision. We, as a dedicated manufacturer and supplier in China, offer not only competitive pricing but also the assurance of consistent quality and adherence to strict manufacturing standards. Our commitment extends to providing detailed product specifications, Certificates of Analysis (COA), and reliable delivery. By choosing to purchase 1-Methyl-L-4,5-dihydroorotic acid from us, you are partnering with an entity that understands the demands of the pharmaceutical industry and is equipped to meet them.

Exploring Further Applications and Research Avenues

Beyond its established role in Taltirelin synthesis, 1-Methyl-L-4,5-dihydroorotic acid is also noted as a useful research intermediate for the synthesis of other optically pure di-substituted dihydroorotic acids and related derivatives. This opens avenues for novel drug discovery and development, where precise molecular structures are key. If your research involves chiral synthesis or the development of new compounds within the pyrimidine series, consider adding this versatile intermediate to your procurement list.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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