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The pharmaceutical industry is in constant pursuit of novel therapeutics, and the synthesis of complex organic molecules forms the backbone of this endeavor. Within this landscape, specialized chemical intermediates play an indispensable role, enabling the precise construction of active pharmaceutical ingredients (APIs). One such crucial intermediate is 3,5-Bis(trifluoromethyl)benzeneboronic acid, readily identifiable by its CAS number 73852-19-4. As a leading chemical manufacturer and supplier, we understand its significance and are dedicated to providing this high-quality compound to researchers and production facilities worldwide.
3,5-Bis(trifluoromethyl)benzeneboronic acid is a trifluoromethylated phenylboronic acid derivative. The presence of two electron-withdrawing trifluoromethyl (CF3) groups on the aromatic ring significantly influences its chemical properties. These groups can enhance the stability of the molecule, alter its reactivity, and, when incorporated into a larger drug structure, can profoundly affect its pharmacokinetic and pharmacodynamic profiles. This makes it an exceptionally valuable building block in medicinal chemistry.
Its primary application in pharmaceutical synthesis is as a coupling partner in palladium-catalyzed cross-coupling reactions, such as the Suzuki-Miyaura reaction. This reaction is a cornerstone of modern organic synthesis, allowing for the efficient formation of carbon-carbon bonds between aryl or vinyl halides and organoboron compounds. By utilizing 3,5-Bis(trifluoromethyl)benzeneboronic acid, medicinal chemists can introduce the 3,5-bis(trifluoromethyl)phenyl moiety into potential drug candidates. This structural element can be strategically employed to:
Given these critical roles, the demand for reliable sources of 3,5-Bis(trifluoromethyl)benzeneboronic acid is substantial. For pharmaceutical companies, securing a consistent supply of high-purity intermediates is vital for both R&D and commercial production. When looking to buy this compound, it is essential to partner with a manufacturer that prioritizes stringent quality control and offers transparency regarding product specifications, such as the common purity of 97% min. Understanding the chemical formula (C8H5BF6O2) and molecular weight (257.93 g/mol) also aids in proper stoichiometric calculations for synthesis.
Our commitment as a supplier extends beyond just providing the chemical. We aim to support the pharmaceutical development pipeline by offering intermediates that meet rigorous industry standards. By choosing us as your manufacturer and supplier for 3,5-Bis(trifluoromethyl)benzeneboronic acid, you are investing in the quality and reliability that your complex synthesis projects demand. We encourage you to inquire about our product and how we can contribute to your next pharmaceutical breakthrough.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
