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The Role of 4-Iodoaniline in API Synthesis: A Supplier's Perspective

The pharmaceutical industry relies heavily on a diverse array of chemical intermediates to synthesize Active Pharmaceutical Ingredients (APIs). Among these, 4-Iodoaniline (CAS 540-37-4) stands out as a versatile and essential building block. As a dedicated manufacturer and supplier in China, we understand the stringent demands of API synthesis and are committed to providing a high-quality product that meets these needs.

Understanding the Chemical Reactivity of 4-Iodoaniline

4-Iodoaniline (C6H6IN, CAS 540-37-4) is characterized by an iodine atom attached to the para position of an aniline ring. This iodine substituent is an excellent leaving group, making the compound highly amenable to a variety of metal-catalyzed cross-coupling reactions. These reactions are fundamental in constructing complex organic molecules required for APIs. Key reactions include:

  • Suzuki-Miyaura Coupling: Reacting 4-iodoaniline with boronic acids or esters to form new carbon-carbon bonds, crucial for creating intricate molecular skeletons.
  • Heck Reaction: Coupling with alkenes to introduce unsaturated functionalities.
  • Sonogashira Coupling: Combining with terminal alkynes to form new carbon-carbon triple bonds.
  • Buchwald-Hartwig Amination: Facilitating the formation of C-N bonds, useful for creating diarylamines and related structures common in pharmaceuticals.

These reactions allow chemists to precisely assemble complex drug molecules, making 4-iodoaniline a cornerstone intermediate for drug discovery and development.

Benefits of Sourcing from Our China Manufacturing Facility

For pharmaceutical companies and contract manufacturing organizations (CMOs), securing a reliable supply of high-purity 4-Iodoaniline is critical. Here’s why partnering with us as your China manufacturer offers significant advantages:

  • Guaranteed Purity: Our 4-Iodoaniline (CAS 540-37-4) is produced under strict quality control measures to achieve purity levels of 98% and above, ensuring minimal side reactions and high yields in API synthesis.
  • Scalable Production: We have the capacity to meet both R&D scale and commercial production volumes, ensuring a seamless transition as your API projects advance. Our productivity is geared towards fulfilling substantial orders from global buyers.
  • Cost-Effectiveness: As a direct manufacturer, we offer competitive pricing for 4-iodoaniline, helping you reduce the overall cost of API production. We provide clear price structures for various quantities.
  • Supply Chain Reliability: Our robust manufacturing operations and efficient logistics network guarantee consistent supply and timely delivery, crucial for maintaining pharmaceutical production schedules. We are a dependable supplier for your raw material needs.
  • Technical Expertise: We provide comprehensive product information and are available for inquiries regarding the use and handling of 4-iodoaniline in your specific synthetic routes.

By choosing us as your supplier for 4-Iodoaniline (CAS 540-37-4), you gain a strategic partner dedicated to supporting your API synthesis endeavors with quality, reliability, and value. We invite you to contact us for a quote and sample to experience the difference.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
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