In the dynamic field of organic synthesis and research and development, the availability of versatile chemical building blocks is indispensable. 4-Methoxyphenylethylamine (CAS 55-81-2) stands out as such a compound, valued for its specific chemical structure and reactivity. This article aims to provide researchers and chemists with a comprehensive overview of its properties, applications in synthesis, and how to effectively purchase it from chemical suppliers, with a focus on manufacturers in China.

Chemical Profile of 4-Methoxyphenylethylamine

4-Methoxyphenylethylamine, identified by CAS number 55-81-2, possesses the molecular formula C9H13NO and a molecular weight of 151.21. Typically presented as a clear, colorless to slightly yellow liquid, it is appreciated for its high purity, often exceeding 97%. Key physical parameters such as its boiling point (138-140 °C at 20 mmHg) and density (1.031 g/mL at 20 °C) are vital for chemists to consider during reaction planning and execution. Its basicity, indicated by a predicted pKa of 9.96, also plays a role in its chemical behavior.

Applications Beyond Pharmaceuticals

While its role as a pharmaceutical intermediate, particularly in the synthesis of ritodrine, is well-documented, the utility of 4-Methoxyphenylethylamine extends into broader organic synthesis. Its structure, featuring a primary amine and a methoxy-substituted phenyl ring connected by an ethyl chain, allows for a variety of chemical transformations. Researchers can leverage this compound in reactions such as derivatization, polymerization, and the creation of novel heterocyclic compounds. Its incorporation into polymeric matrices for electrochemical applications, as noted in some studies, also points to its potential in materials science.

Sourcing Strategies for Researchers and Chemists

For scientists looking to buy 4-Methoxyphenylethylamine for their research projects, reliable sourcing is critical. The global chemical market offers numerous options, with China being a prominent source for specialty chemicals and intermediates. When selecting a supplier, it is important to prioritize those who provide detailed product specifications, safety data sheets (SDS), and Certificates of Analysis (CoA). Engaging with manufacturers directly can provide insights into production capabilities and quality control processes.

Purchasing Considerations: Quality and Value

The cost-effectiveness of research chemicals is a significant consideration for R&D budgets. By sourcing 4-Methoxyphenylethylamine from manufacturers in China, researchers can often access high-purity materials at competitive prices. Many suppliers offer small quantities suitable for laboratory use and also provide bulk pricing for larger-scale research or pilot projects. It is advisable to request samples to verify the quality and suitability of the material for your specific synthetic route before making a substantial purchase.

Conclusion

4-Methoxyphenylethylamine (CAS 55-81-2) is a versatile chemical intermediate with significant applications in pharmaceutical synthesis and broader organic chemistry research. By understanding its chemical properties and focusing on reliable manufacturers and suppliers, particularly those based in China, researchers can ensure access to high-quality materials at favorable prices. This strategic approach to sourcing empowers innovation and successful execution of complex synthetic projects.