In the dynamic field of pharmaceutical research and development, specialized chemical intermediates play a pivotal role. One such compound, (5-Chloro-1,3-diMethyl-1H-pyrazol-4-yl)(2-fluorophenyl)Methanone (CAS 29938-71-4), has garnered attention for its specific applications. For R&D scientists and procurement managers, understanding its utility and how to procure it reliably is essential.

Chemical Profile and Properties

(5-Chloro-1,3-diMethyl-1H-pyrazol-4-yl)(2-fluorophenyl)Methanone, with the molecular formula C12H10ClFN2O, is characterized by its pyrazole and fluorophenyl ketone structure. Its CAS number, 29938-71-4, is the key identifier for global sourcing. Typically supplied with a purity of ≥95%, this light pink crystalline substance offers consistent quality for demanding research applications. Predicted physical properties, such as boiling point and density, are important for handling and process design.

Significance in Pharmaceutical Synthesis

The primary application driving demand for (5-Chloro-1,3-diMethyl-1H-pyrazol-4-yl)(2-fluorophenyl)Methanone is its role as a key intermediate in synthesizing Zolazepam metabolites. Zolazepam is an anxiolytic and anticonvulsant drug, and understanding its metabolic pathways is crucial for pharmacological research, efficacy studies, and potential drug design modifications. The availability of high-purity (5-Chloro-1,3-diMethyl-1H-pyrazol-4-yl)(2-fluorophenyl)Methanone from reputable chemical manufacturers ensures that research endeavors are built upon a solid foundation of quality starting materials.

Research Applications and Safety Considerations

Beyond its synthetic utility, this compound has also been noted for its mutagenic properties in certain *in vitro* assays, such as the Ames test (TA98 and TA100). This characteristic makes it a valuable tool for researchers in toxicology, genotoxicity studies, and cancer research. When working with such compounds, it is vital to adhere to all safety guidelines and handle them in appropriately equipped laboratory environments. Procurement managers should ensure that their chosen supplier can provide comprehensive Safety Data Sheets (SDS).

Where to Purchase and Obtain a Quote

For scientific institutions and pharmaceutical companies looking to purchase (5-Chloro-1,3-diMethyl-1H-pyrazol-4-yl)(2-fluorophenyl)Methanone, several suppliers offer this product. When searching, use terms like 'buy CAS 29938-71-4', 'pharmaceutical intermediate supplier', or 'research chemical manufacturer'. Many suppliers, particularly those based in China, offer competitive pricing and flexible packaging options, often starting from 1kg with bulk discounts available. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier, ready to provide a detailed quote and facilitate your purchase of this critical research chemical.

Conclusion

The role of (5-Chloro-1,3-diMethyl-1H-pyrazol-4-yl)(2-fluorophenyl)Methanone in pharmaceutical R&D, particularly in the synthesis of Zolazepam metabolites and in toxicological research, underscores its importance. By partnering with reliable manufacturers and understanding the product's specifications, researchers can ensure the success of their scientific investigations.