20 YEARS OF PROFESSIONAL & DEDICATED SERVICE TO GLOBAL CUSTOMERS

Custom Manufacturing, Project Outsourcing, your Trusted Partner from China

The Role of Acadesine in Enhancing Cellular Metabolism

NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing high-quality pharmaceutical intermediates, and Acadesine stands out as a compound of significant scientific interest. Acadesine, also known as AICAR or AICA Riboside, is a powerful activator of AMP-activated protein kinase (AMPK). AMPK is a crucial enzyme that acts as a cellular energy sensor, playing a vital role in regulating metabolism at the cellular level. By activating AMPK, Acadesine can influence various metabolic processes, making it a subject of extensive research in fields such as diabetes, cardiovascular health, and exercise physiology.

The primary mechanism through which Acadesine operates is by mimicking the effects of AMP, thereby signaling a low energy state within the cell. This signal triggers a cascade of metabolic adaptations aimed at restoring energy balance. One of the most well-documented effects is the enhancement of glucose uptake in skeletal muscle. This is achieved through the translocation of GLUT-4 transporters to the cell membrane, a process critical for managing blood glucose levels. For researchers looking to explore these effects, understanding the Acadesine CAS number (2627-69-2) is paramount for accurate sourcing and experimental design. The ability to buy Acadesine powder from reliable suppliers ensures the integrity of research findings.

Beyond glucose metabolism, Acadesine's activation of AMPK has implications for lipid metabolism as well. It can promote fatty acid oxidation and inhibit fatty acid synthesis, contributing to a more efficient energy utilization profile. This dual action on glucose and lipid metabolism makes Acadesine a compelling compound for studies related to metabolic syndrome, obesity, and type 2 diabetes. The detailed Acadesine powder applications are continuously being uncovered through ongoing scientific inquiry, highlighting its broad utility in metabolic research.

Furthermore, Acadesine has garnered attention for its potential cardioprotective effects. Research suggests that it can protect the heart from ischemic injury by preconditioning the tissue and reducing inflammatory responses. The AMPK activator mechanism is believed to play a central role in these protective effects, potentially by reducing oxidative stress and improving mitochondrial function. NINGBO INNO PHARMCHEM CO.,LTD. supports these research efforts by supplying high-purity Acadesine, essential for reproducible results in both in vitro and in vivo studies. Exploring the various Acadesine research uses provides valuable insights into its therapeutic potential.

The scientific community's interest in Acadesine extends to its effects on muscle fiber type conversion and endurance. Studies have indicated that Acadesine can promote a shift towards slower, more fatigue-resistant muscle fibers, mimicking some of the benefits of exercise. This has led to its classification as an 'exercise mimetic.' However, it's important to note that Acadesine is on the World Anti-Doping Agency (WADA) prohibited list due to its potential for performance enhancement. Researchers and athletes must be aware of these regulations. For those seeking to conduct rigorous scientific investigation, procuring Acadesine from reputable sources like NINGBO INNO PHARMCHEM CO.,LTD. is crucial for obtaining pharmaceutical grade material.

In summary, Acadesine is a multifaceted compound with significant implications for cellular metabolism, cardiovascular health, and exercise science. Its ability to activate AMPK makes it an invaluable tool for researchers aiming to understand and potentially treat a range of metabolic and ischemic conditions. NINGBO INNO PHARMCHEM CO.,LTD. is committed to facilitating this research by providing high-quality Acadesine powder, enabling scientists to push the boundaries of pharmaceutical innovation.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
SEND US AN EMAIL

NAME*

EMAIL*

COMPANY

COUNTRY*

MESSAGE*

Previous: The Science Behind Better Diabetes Management: Repaglinide Sourcing

Next: Acadesine in Oncology: Targeting Leukemia and Beyond

All Rights Reserved