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Fluorinated organic compounds have become indispensable tools in modern chemistry, particularly within the pharmaceutical and agrochemical industries. The unique electronic and steric properties imparted by fluorine atoms can dramatically influence a molecule's lipophilicity, metabolic stability, and binding affinity. Among these valuable compounds, 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone (CAS 86404-63-9) stands out as a versatile building block. As a leading manufacturer and supplier from China, NINGBO INNO PHARMCHEM CO.,LTD. recognizes the growing demand for such sophisticated chemical intermediates.
The strategic placement of two fluorine atoms on the phenyl ring in 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone enhances its reactivity and alters its electronic distribution, making it a prime candidate for various synthetic pathways. This compound serves as a crucial intermediate, especially in the development of antifungal medications. Its triazole moiety is a common pharmacophore found in many azole antifungals, which inhibit ergosterol biosynthesis in fungi, a vital component of their cell membranes. Therefore, the ability to reliably buy this specific fluorinated acetophenone is critical for pharmaceutical companies engaged in antifungal drug discovery and production.
For R&D scientists and procurement managers, understanding the 'price' and 'availability' of such specialized chemicals is key. Sourcing from an established 'supplier in China' like NINGBO INNO PHARMCHEM CO.,LTD. often provides an advantage in terms of both cost and accessibility for bulk orders. We ensure that our 'pharmaceutical intermediate' offerings, including CAS 86404-63-9, are manufactured to high purity standards, meeting the exacting demands of global pharmaceutical research and development. Our commitment extends to providing consistent supply, flexible payment options, and efficient logistics, making the 'purchase' process as seamless as possible for our international clientele.
The incorporation of fluorine into organic molecules is a well-established strategy to improve pharmacokinetic profiles and enhance therapeutic efficacy. Compounds like 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone exemplify this principle, offering a potent combination of structural features for advanced synthesis. Whether you are investigating novel antifungal agents or exploring new synthetic routes, partnering with a dependable chemical manufacturer is essential.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
