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The Role of ODM-201 in Overcoming AR Resistance in Prostate Cancer

The challenge of androgen receptor (AR) resistance is a central issue in the treatment of advanced prostate cancer, particularly castration-resistant prostate cancer (CRPC). As cancer cells evolve, they can develop mutations or alter AR signaling pathways, rendering previously effective therapies obsolete. Understanding these resistance mechanisms is key to developing more effective treatments, and compounds like ODM-201 are at the forefront of this effort. As a dedicated provider of advanced pharmaceutical intermediates, we are proud to offer ODM-201 to researchers and developers globally.

ODM-201 (CAS: 1297538-32-9) distinguishes itself as a potent AR inhibitor that actively combats known resistance mechanisms. Preclinical studies have highlighted its efficacy against specific AR mutations, such as F876L, which have been identified as critical drivers of treatment failure with second-generation antiandrogens. By maintaining its antagonistic function even in the presence of these mutations, ODM-201 offers a crucial therapeutic option for patients who have exhausted other treatment avenues. This makes it a vital pharmaceutical intermediate for companies focused on innovative oncology solutions.

The development of AR resistance is a complex biological process, and the discovery of compounds like ODM-201, which can effectively bypass these resistance pathways, is a significant step forward. Its demonstrated preclinical success in inhibiting tumor growth and its favorable safety profile, particularly its low brain penetration, further underscore its potential as a valuable therapeutic agent. For pharmaceutical companies and research institutions, securing a consistent supply of high-quality ODM-201 is essential for advancing their clinical pipelines.

We serve as a reliable manufacturer and supplier of ODM-201 from China, committed to delivering products that meet the highest scientific and quality standards. If your work involves prostate cancer research or the development of novel AR-targeted therapies, we encourage you to explore the benefits of incorporating ODM-201 into your studies. Contact us to learn more about our manufacturing capabilities, product availability, and to obtain a quote for your procurement needs. Partner with us to access this critical pharmaceutical intermediate and contribute to the fight against prostate cancer.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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