In the intricate world of chemical synthesis, the strategic use of intermediates is what drives innovation and efficient production. 4-Amino-3-butoxybenzoic Acid, identified by CAS number 23442-22-0, stands out as a crucial organic compound with versatile applications, particularly within the pharmaceutical and fine chemical sectors. Understanding its chemical properties and reactivity is fundamental for any R&D scientist or formulation chemist looking to purchase this valuable building block.

Chemical Identity and Properties

4-Amino-3-butoxybenzoic Acid, with the molecular formula C11H15NO3 and a molecular weight of 209.24 g/mol, features a benzoic acid core substituted with both an amino (-NH2) and a butoxy (-O-(CH2)3CH3) group. These functional groups impart specific chemical behaviors:

• Amino Group: The amine functionality offers nucleophilic character, making it susceptible to acylation, alkylation, and diazotization reactions. This is a key reactive site for introducing nitrogen-containing moieties into larger molecules.
• Carboxylic Acid Group: The carboxylic acid (-COOH) group is acidic and readily undergoes esterification, amide formation, and salt formation. It provides a handle for further functionalization or for forming linkages.
• Butoxy Group: The butoxy substituent contributes lipophilicity to the molecule, influencing its solubility and partitioning behavior in different solvent systems. It also offers some steric influence on reactions occurring at adjacent positions on the aromatic ring.

The molecule's structure suggests moderate lipophilicity (LogP ~2.79) and it exhibits pH-dependent solubility, becoming more hydrophilic at physiological pH due to the ionization of the carboxylic acid. Its high boiling point (around 383.5 °C) indicates strong intermolecular forces, typical for such substituted aromatic compounds.

Synthetic Applications and Commercial Importance

The presence of these reactive functional groups makes 4-Amino-3-butoxybenzoic Acid an excellent precursor for a wide array of syntheses. It is commonly used as:

• A Pharmaceutical Intermediate: For the synthesis of APIs where specific aromatic amine or benzoic acid derivatives are required. Researchers frequently buy this compound to explore novel drug candidates.
• A Fine Chemical Building Block: In the creation of specialty chemicals, dyes, or advanced materials where its unique structural elements can be incorporated.

As a sought-after intermediate, manufacturers and suppliers of 4-Amino-3-butoxybenzoic Acid play a critical role in the chemical industry. For businesses looking to secure this compound, identifying reliable suppliers in China who offer high purity and competitive pricing is essential for both research and large-scale manufacturing operations. If you are interested in purchasing this compound, reaching out to established chemical manufacturers for quotes and specifications is the first step.