Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
NINGBO INNO PHARMCHEM CO.,LTD. understands that the journey from a basic chemical compound to a life-saving medication is a complex one, heavily reliant on critical intermediates. Among these, 4-Chloro-3-nitro-5-sulfamoylbenzoic acid, identified by its CAS number 22892-96-2, stands out as a particularly important player in the pharmaceutical industry. Its primary claim to fame is its indispensable role in the synthesis of Bumetanide, a potent loop diuretic widely prescribed for managing edema associated with heart failure, liver cirrhosis, and kidney disease. The precise chemical structure and purity of this intermediate directly influence the efficacy and safety of the final Bumetanide product.
The synthesis of Bumetanide involves several intricate chemical steps, and 4-Chloro-3-nitro-5-sulfamoylbenzoic acid serves as a foundational building block. Its specific functional groups, including the sulfonamide and nitro substituents on a benzoic acid core, are precisely what the subsequent reaction steps require to build the final Bumetanide molecule. The demand for high-purity pharmaceutical intermediates like this is driven by stringent regulatory requirements, such as those set by the FDA, which necessitate robust quality control and detailed documentation, including Drug Master Files (DMFs) and Abbreviated New Drug Applications (ANDAs). NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing these essential materials with the highest standards of quality and compliance, ensuring our clients can meet these rigorous demands.
Beyond its direct application in Bumetanide manufacturing, the exploration of 4-Chloro-3-nitro-5-sulfamoylbenzoic acid as a versatile intermediate continues in pharmaceutical research. Its complex structure offers opportunities for synthetic chemists to create novel drug candidates with potentially diverse therapeutic applications. The ability to reliably source and utilize such advanced intermediates is a cornerstone of modern pharmaceutical innovation. For manufacturers and researchers seeking to purchase this critical compound, understanding its properties and reliable suppliers is paramount. NINGBO INNO PHARMCHEM CO.,LTD. offers this crucial chemical, supporting the continuous advancement of pharmaceutical science and patient care.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
