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The Role of (S)-2-Amino-5-methoxytetralin Hydrochloride in API Synthesis

The journey from a promising molecule to a marketable drug is paved with complex chemical synthesis, where the quality of each intermediate plays a pivotal role. For Active Pharmaceutical Ingredient (API) synthesis, precision and purity are paramount, and compounds like (S)-2-Amino-5-methoxytetralin Hydrochloride (CAS 58349-17-0) exemplify this principle. This article delves into the significance of this intermediate, its applications, and how to secure a reliable supply from expert manufacturers.

(S)-2-Amino-5-methoxytetralin Hydrochloride is particularly recognized for its indispensable role in the synthesis of Rotigotine, a widely used medication for Parkinson's disease. The specific stereochemistry ('S' configuration) of this amine is critical for the biological activity of Rotigotine. Therefore, manufacturers producing this intermediate must adhere to stringent quality controls to ensure high enantiomeric purity and minimize the presence of unwanted isomers or other impurities. For an R&D scientist, sourcing a reliable batch means ensuring that the subsequent synthesis steps will proceed as expected, leading to a pure and effective API.

When considering the purchase of CAS 58349-17-0, procurement managers look for manufacturers who can guarantee consistent quality and a stable supply chain. This often involves looking for suppliers based in regions with strong chemical manufacturing infrastructure, such as China, known for its extensive network of API and intermediate producers. Identifying a 'reliable manufacturer of pharmaceutical intermediates' means finding a partner that understands the rigorous demands of the pharmaceutical industry. This includes providing detailed product specifications, Certificates of Analysis (CoAs), and potentially support with regulatory documentation.

The search for 'high purity (S)-2-Amino-5-methoxytetralin Hydrochloride for sale' should lead buyers to companies that specialize in fine chemicals and pharmaceutical intermediates. These suppliers often offer competitive pricing for bulk orders, which is crucial for cost-effective API manufacturing. Furthermore, establishing direct communication with a manufacturer, rather than going through multiple intermediaries, can streamline the inquiry process, offer clearer insights into pricing, and facilitate timely delivery. Understanding the available 'price of CAS 58349-17-0' from direct manufacturers is a key part of strategic sourcing.

In conclusion, the successful synthesis of APIs like Rotigotine hinges on the availability of high-quality intermediates such as (S)-2-Amino-5-methoxytetralin Hydrochloride. By prioritizing purity, partnering with experienced manufacturers, and employing robust procurement strategies, pharmaceutical companies can ensure the integrity and efficacy of their final drug products.

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