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In the sophisticated field of pharmaceutical synthesis, specific chemical intermediates act as the foundational building blocks for life-saving medications. (R)-9-(2-hydroxypropyl)adenine, identified by its CAS number 14047-28-0, is one such critical compound. For R&D scientists and formulation experts, understanding its properties and applications is key to advancing antiviral therapies, particularly in the production of tenofovir.
What is (R)-9-(2-hydroxypropyl)adenine?
(R)-9-(2-hydroxypropyl)adenine is a nucleoside analog intermediate. Its molecular formula, C8H11N5O, and a molecular weight of 193.21 indicate a complex structure that is essential for chiral synthesis. The compound is typically a white to off-white crystalline powder, and its precise stereochemistry, denoted by the (R) designation, is critical for its function in drug synthesis.
A Cornerstone for Tenofovir Production
The primary significance of (R)-9-(2-hydroxypropyl)adenine lies in its role as a key precursor in the synthesis of tenofovir. Tenofovir is a potent nucleotide reverse transcriptase inhibitor (NRTI) widely used in the treatment regimens for Human Immunodeficiency Virus (HIV) infection and chronic Hepatitis B virus (HBV) infection. The multi-step synthesis of tenofovir relies on intermediates like (R)-9-(2-hydroxypropyl)adenine to construct the molecule with the correct stereochemical configuration, which is vital for its biological activity.
Why Sourcing Matters for R&D
For researchers and scientists, the quality and availability of this intermediate directly impact the success of their drug development programs. When you buy (R)-9-(2-hydroxypropyl)adenine, consider the following:
The Global Supply Landscape
Many global pharmaceutical companies source essential intermediates from specialized chemical manufacturers. Countries like China are major hubs for the production of these critical compounds. Identifying a trusted (R)-9-(2-hydroxypropyl)adenine manufacturer in China can provide access to high-quality materials at competitive prices, supporting both early-stage research and large-scale commercial production. Companies that specialize in fine chemicals and pharmaceutical intermediates are well-positioned to meet the stringent demands of the global pharmaceutical market.
In conclusion, (R)-9-(2-hydroxypropyl)adenine (CAS 14047-28-0) is more than just a chemical; it's a critical enabler for antiviral therapies. For scientists and researchers, careful selection of suppliers who can provide consistent, high-quality material is a crucial step in the journey from laboratory synthesis to life-saving medicine.
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