Rosuvastatin Calcium, identified by its CAS number 147098-20-2, stands as a cornerstone active pharmaceutical ingredient (API) in the global fight against cardiovascular disease. As a member of the statin class of drugs, it is renowned for its potent effects on lowering harmful cholesterol levels. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to producing this vital compound as a high-purity white powder, ensuring that pharmaceutical manufacturers have access to a superior quality raw material for their formulations.

Mechanism of Action and Efficacy
The primary function of Rosuvastatin Calcium is to selectively inhibit HMG-CoA reductase. This enzyme plays a rate-limiting role in the metabolic pathway that produces cholesterol in the liver. By blocking this enzyme, Rosuvastatin Calcium significantly curtails the liver's ability to synthesize cholesterol. This action triggers a dual response: firstly, it prompts an increase in the number of LDL receptors on the surface of liver cells, which enhances the clearance of low-density lipoprotein (LDL, or 'bad' cholesterol) from the bloodstream. Secondly, it inhibits the liver's synthesis of very-low-density lipoprotein (VLDL), the precursor to LDL. The cumulative effect is a substantial reduction in total cholesterol, LDL cholesterol, and triglycerides, alongside a modest increase in high-density lipoprotein (HDL, or 'good' cholesterol).

Pharmaceutical Applications
The principal application of Rosuvastatin Calcium powder is in the formulation of medications for treating hypercholesterolemia (high cholesterol) and mixed dyslipidemia. These conditions are major risk factors for the development of atherosclerosis, a disease where plaque builds up inside the arteries, leading to serious cardiovascular events such as heart attacks and strokes. Due to its high efficacy, Rosuvastatin Calcium is a preferred choice for clinicians aiming to help patients achieve their target cholesterol levels and reduce their overall cardiovascular risk.

Commitment to Quality from a Leading Manufacturer
As a premier manufacturer of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. ensures that every batch of Rosuvastatin Calcium API meets the most stringent quality and purity standards. Our production process is meticulously controlled to yield a consistent, high-purity (≥99.0%) white to off-white powder, free from contaminants and impurities. We understand that the quality of the API directly impacts the safety and efficacy of the final medicinal product. Therefore, our commitment to excellence is unwavering, from sourcing raw materials to final packaging.

For pharmaceutical companies looking to buy a reliable source of this critical API, we stand as a leading supplier in the market. We provide comprehensive documentation and support to facilitate your formulation and registration processes. If you are seeking a competitive price for Rosuvastatin Calcium or wish to purchase bulk quantities, our team is ready to meet your requirements with professionalism and efficiency. By choosing us, you are partnering with a company that prioritizes quality, consistency, and customer satisfaction in the critical field of life-saving medicines.