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(S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate: A Vital Clopidogrel Intermediate

In the complex landscape of pharmaceutical synthesis, certain chemical intermediates stand out due to their critical role in the production of life-saving medications. Among these, (S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate Salt, identified by its CAS No. 141109-15-1, is a paramount compound. This white crystalline solid is not merely a chemical but a foundational building block for the synthesis of Clopidogrel, a widely recognized antithrombotic agent.


Known by various synonyms such as L-(+)-o-Chlorophenylglycine methyl ester L-tartrate, this compound boasts a molecular formula of C13H16ClNO8 and a molecular weight of 349.72. Its precise chemical structure and stereochemistry are crucial, ensuring the efficacy and safety of the final pharmaceutical product. The optical rotation, typically around +88° (c=1g/100ml in Methanol), further confirms its specific stereoisomeric form, which is vital for its biological activity as an intermediate.


The primary application of (S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate lies in its indispensable role as an intermediate for Clopidogrel and its various salts, including Clopidogrel sulfate (CAS: 120202-66-6) and Clopidogrel camphorsulfonate (CAS: 120202-68-8). Clopidogrel is a potent antiplatelet drug prescribed to prevent blood clots in patients with heart disease, peripheral artery disease, and stroke. The consistent availability and high quality of this intermediate are therefore paramount to the global healthcare supply chain.


Our commitment to excellence ensures that this product is manufactured to the highest standards. It typically exhibits a purity of ≥99%, with a loss on drying maintained at ≤0.50%. Such stringent specifications guarantee its suitability for demanding pharmaceutical applications. Each batch undergoes rigorous quality control checks to meet or exceed industry standards, ensuring reliability and consistency for our partners in drug development and manufacturing.


For optimal stability and preservation of its chemical integrity, (S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate is best stored in a refrigerator at +4°C. It should be kept in a tightly closed container, away from heat, sparks, flame, and other sources of ignition. A cool, dry, and well-ventilated area, isolated from incompatible substances, is recommended to maintain its pristine quality over extended periods. Standard packaging for bulk quantities typically includes 25kg cardboard drums, though custom packaging solutions can be accommodated based on specific customer requirements.


While handling this chemical, it is important to be aware of its safety profile. It carries warning signals for potential harm if swallowed, and may cause skin and serious eye irritation, as well as respiratory irritation. Proper protective measures, including the use of personal protective equipment and adherence to safety data sheet guidelines, are essential during handling and processing to ensure a safe working environment.


As a dedicated manufacturer and supplier of high-quality pharmaceutical intermediates, we understand the critical needs of the industry. We strive to provide competitive price options while upholding uncompromising quality standards. For those looking to buy or purchase (S)-(+)-2-Chlorophenylglycine Methyl Ester Tartrate, we offer reliable sourcing and efficient global distribution. Our robust production capabilities and quality assurance protocols make us a preferred partner for your pharmaceutical raw material needs. Contact us today to learn more about our product offerings and how we can support your manufacturing processes.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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