(S)-3-Amino-3-phenylpropan-1-ol, identified by its Chemical Abstracts Service (CAS) number 82769-76-4, stands as a pivotal chemical compound in the pharmaceutical and fine chemical industries. This chiral amino alcohol plays an indispensable role as an intermediate in the synthesis of complex organic molecules, particularly within the medicinal chemistry landscape. Its unique stereochemical configuration makes it highly valuable for creating enantiomerically pure drug substances, minimizing unwanted side effects and enhancing therapeutic efficacy.

Chemically, (S)-3-Amino-3-phenylpropan-1-ol has a molecular formula of C9H13NO and a molecular weight of 151.21 g/mol. It typically appears as a colorless viscous liquid or a low melting solid, possessing distinct physical characteristics that are crucial for its handling and application. Key properties include a melting point around 68-69 °C and a boiling point estimated at 273.23 °C at 760 mmHg. Its density is approximately 1.074 g/cm³ at 20 °C, and it has a flash point of 150.5 °C. The compound exhibits slight solubility in common organic solvents like chloroform, DMSO, and methanol, which is important for reaction solvent selection. High purity, typically 97% minimum, is essential for its specialized applications, with some grades reaching 99% or even 98% enantiomeric excess (ee) to ensure the desired stereoselectivity in subsequent reactions.

The primary application of (S)-3-Amino-3-phenylpropan-1-ol lies in its utility as a pharmaceutical raw intermediate. Most notably, it serves as a critical precursor for the synthesis of Dapoxetine, a medication used to treat premature ejaculation. Beyond this specific pharmaceutical pathway, its versatility extends to various other organic synthesis processes, acting as a valuable building block for a wide array of active pharmaceutical ingredients (APIs) and specialty chemicals. Its chiral nature allows for the controlled introduction of specific stereocenters, which is vital in modern drug discovery and development to produce compounds with precise biological activities.

Given its chemical nature, proper handling and storage of (S)-3-Amino-3-phenylpropan-1-ol are paramount. It is classified with hazard statements such as H318 (Causes serious eye damage) and H314 (Causes severe skin burns and eye damage), underscoring the need for stringent safety protocols. Users should always wear appropriate personal protective equipment, including protective gloves, clothing, and eye/face protection. In case of contact, immediate rinsing with water and seeking medical attention are advised. Storage conditions recommend keeping the compound in a cool, dry place under an inert gas atmosphere, such as nitrogen or argon, at temperatures between 2–8 °C, with containers tightly closed when not in use. Adhering to these guidelines ensures both safety and product integrity.

For industries requiring this specialized chemical, securing a reliable manufacturer and supplier of (S)-3-Amino-3-phenylpropan-1-ol is critical. A reputable supplier should offer products with consistent high quality and confirmed purity, backed by comprehensive analytical data. When considering where to purchase this compound, factors beyond just the price are essential, including the manufacturer's track record, production capacity, and ability to provide a free sample for evaluation if required. Bulk quantities are often available, catering to both research and industrial scale production needs. Prospective buyers should always compare options from trusted sources to ensure they acquire a product that meets rigorous industry standards for their sensitive applications. Inquiries for buy or purchase should focus on suppliers demonstrating expertise in chemical synthesis and quality assurance.