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(S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide: Key Pharmaceutical Intermediate

(S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide, identified by its CAS Registry Number 136465-81-1, stands as a pivotal chemical compound in advanced pharmaceutical synthesis. This white crystalline powder, also known by synonyms such as (S)-N-t-butyl decahydro-3-iso-quinolinecarboxamide, is highly valued for its specific chiral configuration, which is essential for the precise development of complex drug molecules. Its unique structure, represented by the molecular formula C14H26N2O and a molecular weight of 238.369, underpins its critical role in the production of vital therapeutic agents.


The physical and chemical properties of (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide are well-defined, ensuring its reliable performance in various synthetic pathways. It typically presents as a white powder with a melting point ranging between 112-115ºC, indicating a high degree of purity and stability. The compound exhibits a boiling point of approximately 401.5±24.0 °C at 760 mmHg and a density of 1.0±0.1 g/cm3. Its flash point is recorded at 146.7±23.0 °C. These characteristics are rigorously monitored to ensure consistent quality and predictable reactivity in sensitive chemical processes.


A primary application of (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide lies in its function as a key intermediate for the synthesis of Saquinavir. Saquinavir (CAS: 127779-20-8) is a potent antiretroviral drug belonging to the class of protease inhibitors, widely utilized in the treatment of Human Immunodeficiency Virus (HIV) infection. The precise stereochemistry of (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide is indispensable for conferring the desired biological activity and specificity to the final Saquinavir molecule. The reliance on such a high-purity intermediate underscores the importance of stringent quality control throughout the manufacturing process.


Ensuring the superior quality and high purity of (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide is paramount for its effective use in pharmaceutical manufacturing. NINGBO INNO PHARMCHEM CO.,LTD. is committed to producing this compound with an assay typically at or above 98.0%, adhering to strict international quality standards. Each batch undergoes rigorous analytical testing to confirm its identity, purity, and physical specifications, providing pharmaceutical developers with a reliable and consistent raw material. Our dedication to excellence supports the integrity and efficacy of downstream drug synthesis.


Proper storage and handling are crucial for maintaining the integrity and efficacy of (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide. It should be stored in a cool, well-ventilated area, protected from direct sunlight and moisture, to preserve its chemical stability. The standard packaging for this product is a 25 kg drum, though custom packaging options are available to meet specific customer requirements. This flexibility ensures that the product is delivered in a format most suitable for diverse operational scales and logistical needs, facilitating efficient inventory management and usage for our clients globally.


As a specialized manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. takes pride in its capability to supply high-quality (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide to the global pharmaceutical industry. Our robust production processes and comprehensive quality management system ensure that we are a dependable supplier for critical chemical intermediates. For those looking to buy (S)-N-tert-Butyldecahydroisoquinoline-3-carboxamide, we offer competitive price options tailored to quantity and specific demands. Our expertise as a leading manufacturer allows us to manage large-scale orders efficiently, providing seamless purchase experiences. We are dedicated to building long-term relationships by offering reliable product availability and exceptional service, supporting your innovation and production requirements.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Address: No.163 Ruiqing Rd.,Ningbo 315000 China
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