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Carubicin, known by its CAS number 50935-04-1, is a compound that continues to fascinate researchers due to its potent biological activity. As an anthracycline antibiotic, its primary mode of action is rooted in its ability to interact with cellular DNA. This interaction is primarily twofold: DNA intercalation and inhibition of topoisomerase II. Understanding these mechanisms is key to appreciating its role in antineoplastic research.
DNA intercalation involves Carubicin inserting itself between the base pairs of the DNA double helix. This physical insertion distorts the DNA structure, interfering with essential processes like DNA replication and transcription. Consequently, this disruption can lead to errors in DNA synthesis and an inability for cells to repair damage, ultimately triggering cell death pathways.
Complementing its intercalation ability, Carubicin is also a potent inhibitor of topoisomerase II. This enzyme is critical for managing the supercoiling of DNA during replication and transcription. By inhibiting topoisomerase II, Carubicin prevents the proper unwinding and re-ligation of DNA strands, leading to DNA breaks. These breaks, when unrepaired, signal the cell to undergo apoptosis. This targeted disruption is what makes Carubicin a valuable compound for researchers studying cell death and cancer progression.
For scientists looking to explore these mechanisms further, sourcing high-purity Carubicin from a reputable manufacturer is essential. When you buy Carubicin, you are investing in a powerful research tool. The availability of this compound from reliable suppliers, often with detailed product specifications, supports robust scientific inquiry.
The ongoing research into compounds like Carubicin highlights the continuous evolution in our understanding of cellular processes and disease. Whether for investigating new therapeutic targets or refining existing treatments, the precise scientific action of Carubicin makes it an enduring subject of study in the pharmaceutical and biomedical fields. If you are seeking to purchase Carubicin for your research, consider a supplier known for quality and consistency.
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
