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Iron is an indispensable mineral for human health, playing a critical role in numerous biological processes, most notably the synthesis of hemoglobin. Hemoglobin, found within red blood cells, is responsible for transporting oxygen from the lungs to the body's tissues. When iron levels are insufficient, the body cannot produce enough hemoglobin, leading to iron deficiency anemia (IDA). Iron Dextran injection is a pharmaceutical intervention designed to address this deficiency by directly providing the body with elemental iron.
Iron Dextran is a complex molecule composed of iron ions bound to dextran, a polysaccharide. This complex is designed to be stable in solution and to be safely administered parenterally. Upon injection, whether intramuscularly or intravenously, the iron dextran complex is absorbed into the systemic circulation. Once in the bloodstream, the iron dextran is gradually released from the complex within the body's reticuloendothelial system, primarily in the liver, spleen, and bone marrow.
Within these tissues, macrophages break down the iron dextran complex, releasing elemental iron (ferrous iron, Fe2+). This released iron is then either stored intracellularly as ferritin or transported via the plasma protein transferrin. Transferrin then carries the iron to the bone marrow, where it is utilized by developing red blood cells for the synthesis of hemoglobin. This process effectively replenishes depleted iron stores and increases the production of healthy red blood cells, thereby improving the blood's oxygen-carrying capacity.
The clinical response to Iron Dextran therapy is typically observed through a rise in reticulocyte count (immature red blood cells) shortly after administration, indicating increased red blood cell production. Subsequently, hemoglobin and hematocrit levels gradually increase, alleviating the symptoms of anemia. Regular monitoring of iron parameters, such as serum ferritin and transferrin saturation, helps healthcare providers assess the effectiveness of the treatment and ensure iron stores are adequately replenished without leading to iron overload.
For medical professionals and institutions seeking to buy Iron Dextran or source high-quality pharmaceutical ingredients, understanding this scientific basis is crucial. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supplying pharmaceutical-grade Iron Dextran that adheres to strict quality standards, supporting the effective treatment of iron deficiency anemia.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
