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The Science Behind Ivermectin: Mechanism of Action in Parasite Control

The effectiveness of Ivermectin powder as a broad-spectrum antiparasitic agent in veterinary medicine stems from its specific and potent mechanism of action. Understanding this science is key to appreciating its role in controlling a wide range of parasitic infections. NINGBO INNO PHARMCHEM CO.,LTD., as a supplier of this vital API, offers insights into its biological activity.

Ivermectin belongs to the macrocyclic lactone class of compounds. Its primary mode of action involves binding to glutamate-gated chloride channels (GluCls) and, to a lesser extent, GABA (gamma-aminobutyric acid)-gated chloride channels. These channels are crucial for nerve impulse transmission in invertebrate parasites. In the presence of Ivermectin, these channels remain open, leading to an influx of chloride ions into the nerve and muscle cells of the parasite.

This influx of chloride ions causes hyperpolarization of the cell membranes, effectively paralyzing the parasite. This paralysis disrupts essential bodily functions, such as feeding, movement, and reproduction, ultimately leading to the death of the parasite. The selective toxicity of Ivermectin is noteworthy; it exhibits a much higher affinity for invertebrate GluCls than for mammalian GABA receptors, which are structurally different. This difference is what makes Ivermectin safe for mammals at therapeutic doses, a crucial factor for its use in veterinary antiparasitic solutions.

The ability to buy Ivermectin powder for animals and administer it effectively relies on this precise biological action. Whether targeting gastrointestinal nematodes, lungworms, or external parasites like mites, the underlying principle remains the same: disruption of nerve and muscle function in the target organism. This broad efficacy across various parasite types makes Ivermectin powder a cornerstone of modern animal health strategies and a key product within veterinary pharmaceutical ingredients.

NINGBO INNO PHARMCHEM CO.,LTD. ensures that the Ivermectin powder we supply meets the highest standards of purity and activity, reflecting the scientific precision required for its application. Our commitment to quality means that formulators can rely on our product to deliver the intended therapeutic effects, contributing to successful animal health management.

For professionals in animal health, a thorough understanding of the science behind Ivermectin powder enhances its judicious use. It allows for informed decisions regarding dosages, treatment protocols, and the selection of appropriate formulations for specific parasitic challenges. Through our dedication to sourcing high purity Ivermectin powder, NINGBO INNO PHARMCHEM CO.,LTD. supports the scientific advancement and practical application of Ivermectin in veterinary care.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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