Landiolol Hydrochloride stands out in the field of cardiovascular medicine due to its precisely engineered pharmacological properties. As a highly selective beta-1 adrenergic antagonist, its mechanism of action is centered on targeting specific receptors within the heart, offering a nuanced approach to managing cardiac rhythm disturbances.
At its core, Landiolol Hydrochloride functions by blocking the effects of catecholamines like adrenaline on the beta-1 receptors of the heart. This action leads to a decrease in heart rate and, to some extent, myocardial contractility. What makes Landiolol Hydrochloride particularly advantageous is its designation as an ultra-short-acting agent. Its elimination half-life is a mere few minutes, achieved through rapid hydrolysis by esterases in the blood and liver. This rapid metabolism means that once the infusion is stopped, the drug's effects subside quickly, allowing for precise control over heart rate, especially in acute and critical care scenarios. This characteristic is a significant benefit for clinicians purchasing this compound for critical interventions.
The beta-1 selectivity of Landiolol Hydrochloride is another key scientific attribute. While many beta-blockers affect both beta-1 and beta-2 receptors, Landiolol's strong preference for beta-1 receptors translates to fewer side effects on the respiratory system, which is mediated by beta-2 receptors. This selectivity is crucial for patients with pre-existing pulmonary conditions, making it a safer option when heart rate control is needed. Researchers and medical professionals value this attribute when considering drug choices and formulations.
The benefits derived from these scientific properties are substantial. Landiolol Hydrochloride provides rapid onset of action, meaning heart rate begins to decrease almost immediately after administration is complete. This is critical in emergency situations. Furthermore, its predictable and rapid inactivation by the body means that adverse effects, should they occur, are generally short-lived. This predictability is a cornerstone of its use in perioperative care and intensive therapy units, areas where continuous monitoring and rapid adjustments are standard practice.
For pharmaceutical companies and contract research organizations, understanding this scientific basis is key to effectively utilizing Landiolol Hydrochloride. As a manufacturer, we provide a high-purity (99% min) pharmaceutical grade product, ensuring that the scientific integrity of your research or product development is maintained. Whether you are a procurement manager looking to buy in bulk or a scientist investigating new therapeutic avenues, the precise science behind Landiolol Hydrochloride makes it an indispensable tool in modern medicine.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.