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NINGBO INNO PHARMCHEM CO., LTD. is dedicated to providing the pharmaceutical industry with high-quality ingredients and insightful information. Today, we focus on Liraglutide, a remarkable peptide that acts as a GLP-1 receptor agonist, and explore the scientific underpinnings of its therapeutic efficacy.
Liraglutide is a synthetic peptide analog of human glucagon-like peptide-1 (GLP-1). Its structure is modified to enhance its stability and duration of action compared to the naturally occurring hormone. The molecule consists of a peptide chain with specific amino acid sequences, to which a fatty acid molecule (palmitic acid) is attached via a glutamic acid spacer. This modification is key to its prolonged activity. The attachment of the fatty acid moiety allows Liraglutide to bind to albumin in the bloodstream, protecting it from rapid degradation by enzymes like dipeptidyl peptidase-4 (DPP-4). This binding also contributes to its slow release and sustained therapeutic effect over a 24-hour period.
As a GLP-1 receptor agonist, Liraglutide functions by activating the GLP-1 receptors found on various cells, including pancreatic beta cells, alpha cells, and neurons in the brain. When Liraglutide binds to these receptors, it elicits a cascade of physiological responses. In the pancreas, it promotes the release of insulin in response to elevated blood glucose levels and inhibits the secretion of glucagon. This glucose-dependent action is crucial for maintaining stable blood sugar levels and preventing hypoglycemia. The mechanism of action for Liraglutide is a testament to sophisticated peptide engineering.
The pharmaceutical applications of Liraglutide are primarily in the treatment of type 2 diabetes and chronic obesity. Its ability to improve glycemic control in diabetes and reduce body weight in obese individuals makes it a versatile therapeutic agent. NINGBO INNO PHARMCHEM CO., LTD. supplies high purity liraglutide powder, ensuring that the active pharmaceutical ingredient meets the stringent standards required for drug formulation. Understanding the properties of liraglutide pharmaceutical grade is essential for drug developers.
Researchers and manufacturers seeking reliable sources for peptide synthesis and supply can depend on NINGBO INNO PHARMCHEM CO., LTD. We understand the complexities of peptide chemistry and the importance of consistent quality. Whether you are looking for liraglutide for type 2 diabetes or seeking solutions for weight management, our commitment to excellence ensures you receive a product that meets your exact specifications. The journey of developing effective peptide-based therapies starts with a trusted peptide powder supplier.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
