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Naphazoline Hydrochloride (CAS 550-99-2) is a compound of significant interest in the pharmaceutical industry, largely due to its powerful vasoconstrictive properties. Delving into the Naphazoline hydrochloride synthesis reveals a sophisticated chemical process that yields a compound with distinct characteristics and applications. Understanding these aspects is crucial for anyone involved in its production or utilization.
The typical Naphazoline hydrochloride synthesis begins with the condensation and cyclization of alpha-naphthalene acetic acid and ethylenediamine. This reaction forms 2-(1-naphthylmethyl)imidazoline, which is then subjected to a salification process, usually by introducing hydrogen chloride gas. This final step yields the crystalline Naphazoline Hydrochloride salt. The purity of the raw materials and precise control over reaction conditions, such as temperature and reaction time, are critical to ensure a high-quality final product with the desired characteristics.
The Naphazoline hydrochloride chemical properties are also noteworthy. It typically presents as a white crystalline powder, possessing good solubility in water and alcohol, which aids in its formulation into various pharmaceutical dosage forms like eye drops and nasal sprays. Its chemical structure, featuring an imidazoline ring and a naphthalene moiety, is key to its pharmacological activity as an alpha-adrenoceptor agonist. Reliable Naphazoline hydrochloride manufacturers ensure these properties are consistent across batches, often backed by rigorous testing and adherence to pharmacopeial standards like USP or EP.
Ningbo Inno Pharmchem Co., Ltd. is a trusted partner for high-purity Naphazoline Hydrochloride, offering products that meet stringent industry specifications. Our expertise in chemical synthesis and commitment to quality assurance ensures that our clients receive a product perfectly suited for their pharmaceutical applications.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
