Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
NINGBO INNO PHARMCHEM CO., LTD. is dedicated to providing pharmaceutical professionals with high-quality excipients like Povidone K30 (PVP K30), accompanied by a deep understanding of the scientific principles that govern its effectiveness. The ability of PVP K30 to enhance drug dissolution and improve overall formulation performance is rooted in its molecular structure and physicochemical properties.
At its core, Povidone K30 is a polymer derived from N-vinylpyrrolidone. Its hydrophilic nature, stemming from the polar amide group in its structure, allows it to readily interact with water and other polar solvents. This property is fundamental to its role as a Povidone K30 solubility enhancer. When PVP K30 is used to form amorphous solid dispersions or coprecipitates with poorly soluble drugs, it creates a more favorable environment for dissolution. The polymer effectively 'shields' the drug molecules, preventing them from aggregating and promoting their dispersion in the dissolution medium. This process significantly increases the effective surface area of the drug, leading to a much faster dissolution rate.
The science behind PVP K30's function as a tablet binder also relates to its polymer chain structure and its ability to form strong hydrogen bonds and van der Waals interactions with APIs and other excipients. During granulation, these interactions create a robust matrix that holds the tablet together, providing the necessary mechanical strength. This is crucial for the successful production of tablets where appropriate PVP K30 pharmaceutical applications are key.
Furthermore, the low solution viscosity of Povidone K30 at high polymer concentrations makes it practical for manufacturing processes. This characteristic, combined with its non-ionic nature, means its solution properties are not easily affected by pH changes or the presence of electrolytes, simplifying formulation development. For manufacturers looking to buy Povidone K30, NINGBO INNO PHARMCHEM CO., LTD. ensures that the product's scientific attributes are consistently maintained, enabling predictable and reliable performance in diverse pharmaceutical applications.
Understanding the science behind Povidone K30—its interactions with APIs, its role in creating amorphous states, and its binding capabilities—allows formulators to maximize its potential. NINGBO INNO PHARMCHEM CO., LTD. is proud to supply this scientifically advanced excipient, contributing to the development of more effective and patient-friendly medications.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
