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Streptomycin sulfate, a powerful aminoglycoside antibiotic, has been a critical weapon against bacterial infections for decades. Understanding its precise mechanism of action and the development of bacterial resistance is key to its continued effectiveness. NINGBO INNO PHARMCHEM CO.,LTD. explores the science behind this vital compound.
At the heart of streptomycin sulfate's action is its interaction with bacterial ribosomes. Specifically, it binds to the 30S ribosomal subunit, a complex molecular machine responsible for protein synthesis. This binding causes a critical error: it induces misreading of the messenger RNA (mRNA) sequence. As bacteria attempt to translate this corrupted genetic code, they produce non-functional or toxic proteins. This disruption of protein synthesis ultimately leads to bacterial cell death. This intricate process, known as the streptomycin mechanism of action, highlights the targeted approach of this antibiotic.
The development of bacterial resistance to antibiotics is a significant global health challenge. For streptomycin sulfate, resistance can arise through several mechanisms. Mutations in genes encoding ribosomal components, such as the 16S rRNA or the S12 ribosomal protein, can alter the streptomycin binding site, reducing the drug's efficacy. Additionally, bacteria can develop enzymes that chemically modify or degrade streptomycin, rendering it inactive. Understanding these mechanisms is crucial for developing strategies to combat antibiotic resistance. This includes using streptomycin sulfate in combination therapies and ensuring adherence to prescribed treatment regimens.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supporting the fight against bacterial resistance by providing high-quality pharmaceutical intermediates like streptomycin sulfate. Researchers and pharmaceutical developers can procure streptomycin sulfate from us for studies aimed at understanding resistance mechanisms and developing new antimicrobial agents. Our products are manufactured to meet stringent purity standards, ensuring reliable results in scientific investigations.
The ongoing research into streptomycin sulfate, its mechanisms, and resistance patterns is vital for maintaining its therapeutic value and developing future treatments. NINGBO INNO PHARMCHEM CO.,LTD. remains a steadfast partner in these critical scientific endeavors.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
