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Sodium Benzoate: A Comprehensive Guide to Its Uses and Safety

Sodium Benzoate, the sodium salt of benzoic acid, stands as a fundamental compound in various industries, primarily renowned for its efficacy as a preservative. This white, odorless, and crystalline powder, with the chemical formula C7H5NaO2 and CAS number 532-32-1, is a synthetic substance. However, its precursor, benzoic acid, occurs naturally in numerous fruits and vegetables, including cranberries, plums, and cinnamon, as well as in fermented dairy products.


The production of Sodium Benzoate typically involves the neutralization of benzoic acid with sodium hydroxide. This process yields a highly soluble compound, making it an ideal additive for liquid and semi-liquid products. Its primary function is to inhibit the growth of undesirable microorganisms such as bacteria, molds, and yeasts, thereby significantly extending the shelf life of products and preventing spoilage.


The applications of Sodium Benzoate are remarkably diverse and critical across several sectors:

Food and Beverage Industry: Sodium Benzoate is one of the earliest preservatives approved for food use and is globally recognized under the E-number E211. It is particularly effective in acidic environments, which is why it's commonly found in products like carbonated soft drinks, fruit juices, salad dressings, pickles, jams, and various condiments. Its inclusion helps maintain the freshness, flavor, and integrity of these items over time, safeguarding them against microbial contamination.

Pharmaceuticals: Beyond its role in food, Sodium Benzoate serves as a crucial preservative in many over-the-counter and prescription medications, especially liquid formulations such as cough syrups. It can also function as a lubricant during pill manufacturing, helping to create smooth, transparent tablets that dissolve efficiently. In larger, controlled doses, it is medically utilized to manage conditions like urea cycle disorders and hyperammonemia, where it aids in reducing elevated blood ammonia levels by facilitating the excretion of amino acids.

Cosmetics and Personal Care: The antimicrobial properties of Sodium Benzoate make it a popular choice for preserving personal care products. It is frequently incorporated into hair products, baby wipes, toothpaste, mouthwashes, moisturizers, and sunscreens, ensuring these items remain safe and free from microbial growth throughout their use-by dates.

Industrial Applications: Industrially, Sodium Benzoate is employed as an anti-corrosive agent, for example, in coolants for car engines. It also finds use in photo processing and can contribute to enhancing the strength of certain plastics, showcasing its wide-ranging utility beyond consumer products.


The preservation mechanism of Sodium Benzoate primarily involves its conversion to benzoic acid within the cell of microorganisms. This lowers the intracellular pH, disrupting metabolic processes crucial for microbial growth and survival, particularly impacting anaerobic fermentation of glucose. This action effectively halts the proliferation of spoilage-causing agents.


Regarding safety, Sodium Benzoate is widely deemed Generally Recognized As Safe (GRAS) by regulatory bodies such as the U.S. Food and Drug Administration (FDA) and the World Health Organization (WHO). The FDA limits its concentration in foods and beverages to a maximum of 0.1% by weight. The human body efficiently metabolizes Sodium Benzoate, combining it with glycine to form hippuric acid, which is then rapidly excreted, typically within 24 hours. The WHO sets an acceptable daily intake (ADI) level of 0–5 mg per kilogram of body weight per day, a level rarely exceeded through normal dietary consumption.


While generally considered safe, some discussions exist regarding potential associations. For instance, in soft drinks containing both Sodium Benzoate and ascorbic acid (Vitamin C), benzene, a known carcinogen, can potentially form. However, after initial findings, manufacturers largely reformulated their products, and current levels found are considered safe by health authorities. Other preliminary studies have explored links to inflammation, ADHD symptoms, and allergies, but more extensive human research is needed to draw definitive conclusions. It is important for consumers to be aware of ingredients and consult healthcare professionals if sensitivities are suspected.


For those looking to secure high-quality Sodium Benzoate, understanding its provenance is key. As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. upholds stringent quality standards, ensuring purity and consistency in every batch. We offer competitive price options for bulk purchase, catering to diverse industrial needs. Our commitment to excellence makes us a reliable partner for companies seeking to buy this essential preservative. We ensure a seamless experience from inquiry to delivery, providing detailed product specifications and supporting clients globally to source this vital chemical with confidence.

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