At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to supplying high-quality chemicals that drive scientific progress. Sodium Dodecyl Sulfate (SDS), also known as Sodium Lauryl Sulfate (SLS), is a chemical compound whose importance in modern laboratory settings cannot be overstated. As a potent anionic surfactant, SDS exhibits unique properties that make it indispensable for a variety of critical scientific investigations, particularly in biochemistry and molecular biology.
Perhaps the most renowned application of SDS in the lab is its integral role in SDS-PAGE (Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis). This technique is a cornerstone for analyzing proteins based on their molecular weight. SDS works by denaturing proteins, disrupting their non-covalent bonds and imparting a uniform negative charge to each polypeptide chain. This ensures that during electrophoresis, proteins migrate through the gel matrix primarily based on their size, allowing researchers to accurately determine molecular masses and assess protein purity. The reliability of laboratory grade Sodium Dodecyl Sulfate is paramount for the accuracy of these results.
Beyond electrophoresis, SDS is frequently employed as a cell lysis agent. In molecular biology, the efficient extraction of nucleic acids (DNA and RNA) or proteins from cells is crucial. SDS effectively disrupts cell membranes and denatures proteins, including nucleases that could degrade genetic material. This makes it an essential component in many lysis buffers, safeguarding the integrity of the biomolecules of interest. Researchers often seek to buy Sodium Dodecyl Sulfate for its efficacy in these preparatory steps.
The consistent performance of SDS as a surfactant also finds utility in general laboratory cleaning protocols. Its ability to break down organic residues and oils makes it effective for cleaning glassware and equipment, ensuring they are free from contaminants that could interfere with sensitive experiments. The demand for high purity Sodium Dodecyl Sulfate is driven by the need for reproducible and reliable experimental outcomes.
In summary, Sodium Dodecyl Sulfate is far more than just a detergent; it is a critical reagent that facilitates groundbreaking research in laboratories worldwide. Its unique surfactant properties, particularly in protein denaturation and cell lysis, solidify its status as an essential tool for scientists pushing the boundaries of knowledge.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
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