In the field of pharmaceutical intermediates, the quality and purity of active pharmaceutical ingredients (APIs) are paramount. NINGBO INNO PHARMCHEM CO.,LTD. is proud to highlight the significance of Sodium Picosulfate (CAS 10040-45-6), a high-efficacy raw material that plays a crucial role in modern gastroenterological treatments. Supplied as a high-purity white powder, this compound is foundational in the formulation of treatments for constipation and for bowel cleansing prior to medical procedures like colonoscopies.

Sodium Picosulfate is a locally acting stimulant laxative. What makes it particularly remarkable is its mechanism of action. It is a prodrug, meaning it is administered in an inactive form. Once it reaches the colon, it is hydrolyzed by gut bacteria into its active metabolite, Bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM). This active compound then directly stimulates the nerve endings in the colonic mucosa, increasing peristalsis and promoting the accumulation of water and electrolytes in the colonic lumen. This results in an effective and predictable laxative effect, which is highly localized to the colon, minimizing upper gastrointestinal side effects.

Key Applications and Benefits
The primary applications for our pharmaceutical-grade Sodium Picosulfate powder are twofold:
1. Bowel Cleansing Preparations: It is a core component in compound preparations, often combined with an osmotic agent like magnesium citrate. These formulations are highly effective for clearing the bowel before colonoscopies, radiological examinations, or abdominal surgeries, ensuring a clean field of view for accurate diagnosis and successful procedures.
2. Chronic Constipation Management: For individuals suffering from chronic functional constipation, Sodium Picosulfate provides reliable relief, particularly when other treatments have proven ineffective. Its targeted action helps restore normal colonic motility.

The quality of the raw material directly impacts the safety and efficacy of the final medicinal product. Our Sodium Picosulfate powder boasts a purity level of over 99%, meeting stringent pharmaceutical standards. This ensures that formulators receive a consistent, reliable, and safe ingredient for their manufacturing processes. The fine white powder appearance and specified characteristics are guaranteed through rigorous quality control and testing, including HPLC assay methods.

For pharmaceutical companies looking to formulate superior digestive health products, sourcing high-quality APIs is the first and most critical step. As a dedicated manufacturer and supplier of pharmaceutical intermediates, we understand the importance of quality and consistency. If you wish to inquire about the price or to purchase our premium Sodium Picosulfate powder, please contact our specialists. Partner with a trusted source to ensure the excellence of your finished products. To get more details or to buy Sodium Picosulfate powder, connecting with a reliable supplier is essential for your procurement needs.