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NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of providing essential pharmaceutical excipients, and Sodium Starch Glycolate (SSG) is a cornerstone of our offerings. This article delves into the intricate role of SSG as a pharmaceutical disintegrant, highlighting its mechanisms of action and the significant advantages it brings to tablet formulations. SSG, a derivative of starch, is specifically engineered to enhance the rate at which tablets break apart when exposed to moisture, thereby facilitating the rapid release and subsequent absorption of the active pharmaceutical ingredient (API).
The primary mechanism by which SSG functions is through rapid hydration and swelling. Upon contact with water, the cross-linked structure of SSG absorbs a significant amount of liquid, leading to a substantial increase in volume. This swelling action generates internal pressure within the tablet matrix, disrupting the inter-particulate bonds and causing the tablet to disintegrate into smaller fragments. This is critical for ensuring that the API becomes readily available for dissolution. Manufacturers seeking to buy Sodium Starch Glycolate in bulk can rely on NINGBO INNO PHARMCHEM CO.,LTD. for consistent quality and supply.
The advantages of using SSG are numerous. It offers excellent disintegrating efficiency, even at low concentrations, making it a cost-effective solution. Unlike some other disintegrants, SSG can also contribute to increasing tablet hardness without detrimentally affecting its disintegration time. This dual benefit is highly sought after in tablet manufacturing. Understanding the benefits of SSG in tablets, such as its ability to improve tablet hardness while maintaining rapid disintegration, is key for successful formulation development. Furthermore, the sodium starch glycolate chemical formula, (C6H9O4Na)n, represents a chemically stable compound that is compatible with a wide range of APIs.
When considering pharmaceutical grade excipient sourcing, reliability and performance are paramount. SSG's hygroscopic nature necessitates careful handling and storage to maintain its optimal functionality. NINGBO INNO PHARMCHEM CO.,LTD. ensures that its SSG products are packaged appropriately to preserve their integrity. The effectiveness of this sodium starch glycolate tablet disintegrant in various formulations, including immediate-release and even some specialized controlled-release systems, underscores its importance in modern pharmaceutical development. We are committed to supporting your formulation needs with high-quality Sodium Starch Glycolate.
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
