For procurement managers, R&D scientists, and formulation chemists in the chemical and pharmaceutical sectors, securing a consistent supply of high-quality raw materials is paramount. 1-Chlorobutane (CAS 109-69-3) is one such compound that plays a crucial role in various synthesis processes. If you are looking to buy 1-Chlorobutane, understanding its properties, applications, and the best sourcing strategies will ensure you make an informed decision.
1-Chlorobutane, also known as n-butyl chloride, is an alkyl halide with the chemical formula C4H9Cl. It is a colorless liquid with a characteristic odor. Its physical properties, such as a boiling point of approximately 78°C and a density of 0.886 g/mL at 25°C, make it suitable for various industrial applications. Its solubility in water is limited, but it is miscible with many organic solvents, making it a useful solvent or reactant in specific chemical reactions.
The primary application of 1-Chlorobutane lies in organic synthesis. It serves as a key intermediate in the production of organometallic compounds, such as n-butyllithium, which is vital for Grignard reactions and other carbon-carbon bond-forming processes. Furthermore, it finds application in the synthesis of other butyl derivatives, including butylamines and butyl ethers. For businesses involved in the development of new agrochemicals or specialty chemicals, sourcing reliable 1-Chlorobutane is essential.
In the pharmaceutical industry, 1-Chlorobutane is utilized in the synthesis of active pharmaceutical ingredients (APIs) and pharmaceutical intermediates. Its specific reactivity allows for targeted modifications and the construction of complex molecular structures required for therapeutic compounds. Researchers and product developers often look for suppliers who can guarantee consistent batch-to-batch quality and purity, especially when dealing with sensitive synthetic pathways.
When considering the purchase of 1-Chlorobutane, understanding its CAS number (109-69-3) is critical for accurate identification and sourcing. Prospective buyers should always inquire about the purity specifications, typically ranging from 99% to 99.5% or higher, and any specific requirements like low water content (e.g., less than 50 ppm by Karl Fischer titration) which are important for moisture-sensitive reactions. Suppliers offering HyDry grades with molecular sieves can be particularly valuable.
For businesses seeking to purchase 1-Chlorobutane in China, it is advisable to partner with established manufacturers and suppliers. These suppliers can often provide competitive pricing for bulk quantities, offer flexible packaging options, and ensure adherence to international quality standards. When seeking a quote, be prepared to specify your required quantities, purity levels, and any special packaging or delivery needs. Companies like NINGBO INNO PHARMCHEM CO.,LTD. specialize in providing these crucial chemical intermediates, understanding the demands of the global market for high-quality and cost-effective raw materials.
In summary, whether for laboratory research or large-scale industrial production, 1-Chlorobutane is a versatile and important chemical. By focusing on quality, reliability, and competitive pricing when selecting a manufacturer and supplier, you can ensure the success of your downstream applications.
Manufacturing Facilities






Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.