In the dynamic world of chemical synthesis, securing a consistent and high-quality supply of essential building blocks is paramount for B2B procurement professionals and R&D scientists. One such critical compound is 2-Chloro-1,4-difluorobenzene, identified by CAS number 2367-91-1. Understanding how to effectively source this fluorinated aromatic compound can significantly impact project timelines and product efficacy. This guide, brought to you by NINGBO INNO PHARMCHEM CO.,LTD., aims to demystify the procurement process for this vital intermediate.

Understanding 2-Chloro-1,4-difluorobenzene (CAS 2367-91-1)

2-Chloro-1,4-difluorobenzene is a key organic intermediate characterized by its unique combination of chlorine and fluorine substituents on a benzene ring. Its chemical formula is C6H3ClF2, and it possesses a molecular weight of approximately 148.54 g/mol. Typically appearing as a liquid, it exhibits a boiling point in the range of 126-128 °C and a flash point of 68 °F (20 °C). For optimal stability, it is recommended to store this chemical in a dry, cool, and sealed environment, protected from air exposure. Its high purity, often exceeding 95%, makes it indispensable for precise chemical reactions.

Key Applications and Their Significance

The versatility of 2-Chloro-1,4-difluorobenzene stems from its fluorinated nature and the presence of a reactive chlorine atom, making it a valuable precursor in several industries. Its primary roles include:

• Pharmaceutical Intermediates: It serves as a crucial building block in the synthesis of various Active Pharmaceutical Ingredients (APIs). The incorporation of fluorine atoms can enhance metabolic stability, lipophilicity, and binding affinity of drug molecules, leading to more effective and potent therapeutics.
• Agrochemicals: In the agrochemical sector, this compound is employed in the development of novel pesticides, herbicides, and fungicides. Fluorinated compounds often exhibit improved efficacy and environmental persistence profiles.
• Material Science: The unique electronic and physical properties imparted by fluorine make 2-Chloro-1,4-difluorobenzene useful in the synthesis of advanced materials, including specialized polymers, liquid crystals, and organic electronic components.

Navigating the Procurement Process: Tips for B2B Buyers

When looking to buy 2-Chloro-1,4-difluorobenzene, B2B professionals should prioritize working with reputable manufacturers and suppliers who can guarantee quality and consistency. Here are some key considerations:

1. Purity Verification: Always request detailed Certificates of Analysis (CoA) to confirm the purity (e.g., 95% min, 98%) and assay of the product. This is critical for ensuring successful synthesis outcomes.
2. Supplier Reliability: Partner with manufacturers known for their robust quality control systems and reliable supply chains. Companies with a strong track record in China often offer competitive pricing and dependable delivery.
3. Price Inquiry for Bulk Orders: For significant quantities, always conduct a thorough price inquiry. Manufacturers are typically willing to negotiate pricing for bulk purchase, making your procurement more economical.
4. Technical Support: Engaging with a supplier that offers technical support can be invaluable, especially when integrating a new intermediate into your processes.
5. Sample Availability: Before committing to a large order, request a free sample to evaluate the product's suitability for your specific application.

Choosing a Manufacturer for 2-Chloro-1,4-difluorobenzene

NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted manufacturer and supplier of 2-Chloro-1,4-difluorobenzene. We are committed to providing high-quality chemical intermediates with stringent quality control measures. Our focus on customer satisfaction, competitive pricing for bulk orders, and reliable supply makes us an ideal partner for your chemical procurement needs. We understand the importance of dependable sourcing for research and industrial applications, and we are dedicated to meeting those demands. If you are looking to purchase 2-Chloro-1,4-difluorobenzene or require a quotation for your specific project, do not hesitate to contact us. We aim to facilitate your procurement with efficiency and expertise, ensuring you receive the best products and services.