For procurement managers and R&D scientists in the pharmaceutical industry, identifying and securing reliable sources for key chemical intermediates is paramount. One such critical compound is 2-Phenoxyethyl Chloride (CAS: 622-86-6), a versatile building block widely utilized in the synthesis of various active pharmaceutical ingredients (APIs). Understanding its properties, synthesis routes, and the importance of a dependable supplier can significantly impact project timelines and cost-efficiency.

Understanding 2-Phenoxyethyl Chloride

Chemically known as 2-Phenoxyethyl Chloride, with the molecular formula C8H9ClO and a molecular weight of 156.61 g/mol, this compound presents itself typically as a white or off-white solid. Its physical properties, such as a boiling point of approximately 219°C and a density of around 1.13 g/mL, are indicative of its suitability for various chemical processes. The presence of both a phenoxy group and a reactive chloroethyl moiety makes it a valuable intermediate for introducing specific functionalities into more complex molecules.

Key Applications in Pharmaceutical Synthesis

The primary driver for the demand of 2-Phenoxyethyl Chloride is its role as an intermediate in the pharmaceutical sector. It is notably used in the synthesis of drugs such as nafazodone, an antidepressant, and derivatives of tamoxifen, a selective estrogen receptor modulator used in breast cancer treatment. Its utility extends to general organic synthesis, where it can participate in a variety of coupling reactions and nucleophilic substitutions, allowing chemists to build intricate molecular structures. For companies looking to buy 2-Phenoxyethyl Chloride, its importance in these established synthetic pathways makes it a staple chemical.

Why Source from a Chinese Manufacturer?

For procurement professionals seeking to buy 2-Phenoxyethyl Chloride, sourcing from a reputable manufacturer in China offers distinct advantages. Chinese chemical manufacturers often provide competitive pricing, owing to economies of scale and efficient production processes. More importantly, established suppliers maintain stringent quality control measures, ensuring product purity (typically ≥98.0%) and low water content (≤0.1%), which are critical for pharmaceutical applications. When searching for a 2-Phenoxyethyl Chloride supplier, it is essential to prioritize those with a proven track record in quality assurance and reliable delivery.

Furthermore, experienced manufacturers understand the importance of regulatory compliance and can provide necessary documentation, such as Certificates of Analysis (CoA) and Material Safety Data Sheets (MSDS). This is vital for pharmaceutical companies that operate under strict regulatory guidelines.

Factors to Consider When Purchasing

When you purchase 2-Phenoxyethyl Chloride, consider the following:

• Purity Level: Ensure it meets the requirements for your specific application, especially for pharmaceutical synthesis.
• Supplier Reliability: Look for manufacturers with consistent production capacity and a history of timely deliveries.
• Pricing and MOQ: Compare prices and minimum order quantities from various suppliers to find the best value.
• Technical Support: A responsive supplier offering technical assistance can be invaluable when troubleshooting synthesis issues.

By carefully selecting your supplier, you can ensure a consistent and cost-effective supply of 2-Phenoxyethyl Chloride, enabling you to focus on innovation and production in your pharmaceutical endeavors. For those seeking a reliable 2-Phenoxyethyl Chloride manufacturer, exploring options within China can lead to significant benefits in both quality and cost.