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For pharmaceutical manufacturers focused on oncology, the reliable sourcing of key intermediates is paramount. One such critical compound is tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate, identified by CAS number 1256584-75-4. This molecule serves as a vital building block in the synthesis of Alectinib, a highly effective anaplastic lymphoma kinase (ALK) inhibitor used in targeted cancer therapy, particularly for certain types of non-small cell lung cancer (NSCLC).
The efficacy and safety of the final pharmaceutical product are directly influenced by the quality of its intermediates. Therefore, understanding the specifications and sourcing from reputable manufacturers is non-negotiable. Tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate is typically supplied as an off-white to white powder, with a high purity level of ≥98.0%. This high purity ensures that subsequent reaction steps are clean and efficient, minimizing the formation of unwanted by-products and simplifying purification processes.
When seeking to purchase this crucial pharmaceutical intermediate, it is essential to identify suppliers who can guarantee consistent quality, competitive pricing, and a robust supply chain. Manufacturers and R&D scientists often look for suppliers in China due to the country's significant role in the global fine chemical and pharmaceutical intermediate market. Engaging with a reliable chemical manufacturer from this region can provide access to both quality products and cost-effective solutions. Asking for a price quote for bulk orders or specific packaging requirements is a standard step for procurement managers.
The role of this specific indole derivative in the Alectinib synthesis pathway highlights the importance of specialized chemical intermediates in modern drug development. Companies that are looking to buy tert-Butyl 6-cyano-2-(2-(4-ethyl-3-iodophenyl)propan-2-yl)-1H-indole-3-carboxylate for their research or manufacturing operations should prioritize suppliers who provide detailed technical data, Certificates of Analysis (CoA), and responsive customer service. Establishing a strong relationship with a trusted supplier is key to maintaining a smooth production flow and achieving the desired therapeutic outcomes for patients.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
