Navigating the landscape of chemical sourcing requires a discerning eye, especially when it comes to materials destined for pharmaceutical applications. 3-Aminophenylacetylene HCl (CAS 207726-02-6), a widely sought-after pharmaceutical intermediate, demands particular attention to quality and supplier reliability. This guide aims to provide insights into sourcing this critical compound effectively, ensuring it meets the stringent requirements for your chemical synthesis needs.

Understanding the Specifications of 3-Aminophenylacetylene HCl

When procuring 3-aminophenylacetylene HCl, several key specifications should be at the forefront of your evaluation:

• Purity: The most critical factor is purity, typically specified as 99% or higher, often verified by HPLC. For pharmaceutical intermediates, even minor impurities can have significant downstream effects on reaction yields and the quality of the final API.
• Appearance: The standard appearance is a white powder, which can serve as an initial visual indicator of quality.
• CAS Number: Always confirm the CAS number is 207726-02-6 to ensure you are obtaining the correct isomer and compound.
• Stability and Storage: While not always detailed in a simple product description, understanding recommended storage conditions (e.g., cool, dry, protected from light) is important for maintaining quality.

These specifications are crucial when searching for suppliers using keywords like 'high purity 3-aminophenylacetylene HCl' or 'pharmaceutical intermediate CAS 207726-02-6'.

Identifying Reliable Manufacturers and Suppliers

The reliability of your supplier directly impacts the consistency and success of your synthesis processes. When sourcing 3-aminophenylacetylene HCl, consider manufacturers that:

• Offer Certificates of Analysis (CoA): A detailed CoA is non-negotiable. It should provide comprehensive analytical data, including purity assays, impurity profiles, and spectroscopic data (e.g., NMR, IR) confirming the compound's identity.
• Have a Proven Track Record: Look for companies with established reputations in the fine chemical and pharmaceutical intermediate market. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. are known for their commitment to quality.
• Provide Scalable Quantities: Ensure the supplier can meet your needs, whether for small-scale R&D or large-scale commercial production.
• Offer Technical Support: A responsive supplier who can provide technical data and support can be invaluable in troubleshooting or optimizing synthesis processes.

Keywords such as 'buy 3-aminophenylacetylene HCl', 'pharmaceutical grade intermediate supplier', or 'API chemical sourcing' can help identify suitable vendors.

The Role of 3-Aminophenylacetylene HCl in Erlotinib Synthesis

As a key side chain intermediate for Erlotinib Hydrochloride, the consistent availability of high-quality 3-aminophenylacetylene HCl is critical for pharmaceutical companies producing this vital oncology drug. Sourcing this intermediate effectively ensures that the complex synthesis of Erlotinib proceeds smoothly, contributing to the reliable supply of this life-saving medication.

In conclusion, a thorough approach to sourcing 3-aminophenylacetylene HCl, focusing on purity, supplier reliability, and documented quality, is essential for any organization involved in pharmaceutical synthesis. By understanding these critical factors, you can secure the high-quality chemical building blocks necessary for successful drug development and manufacturing.